Rabbit Anti-PODXL Recombinant Antibody (VS13-YC915)
CAT#: VS13-YC915
The Rabbit Anti-PODXL Recombinant Antibody is specific for human PODXL. PODXL encodes a sialomucin family member, part of podocytes in kidneys, binding cytoskeletal elements, expressed in various cells, and involved in differentiation. The anti-PODXL antibody can be used for Immunohistochemistry (1/100-1/200).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoli, plasma membrane, centriolar satellites & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2110/118_H1_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoli, plasma membrane & centriolar satellites.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2110/119_H1_1_blue_red_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62558/140923_B_9_5.jpg
Normal Tissue
Figure 4 Kidney
Bowman's capsule
Staining:High
Intensity: Strong
Quantity:>75%
Cells in glomeruli
Staining:High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62558/140923_A_8_5.jpg
Normal Tissue
Figure 5 Endometrium
Glandular cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62558/140923_B_5_3.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (fHDF/TERT166, NTERA-2, SuSa, TIME, U-251 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000128567-PODXL
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Specifications
- Immunogen
- Recombinant human PODXL.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human PODXL
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Atypical Juvenile Parkinsonism; Young-Onset Parkinson Disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.1) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- PC; PDX; PCLP; Gp200; gp135; PCLP-1; PODXL1
- Gene ID
- 5420
- UniProt ID
- O00592
- Long Name
- podocalyxin like
- Cellular Localization
- Apical cell membrane; Cell projection; Lamellipodium
- Protein Refseq
- NP_005388.2
- Function
- Involved in the regulation of both adhesion and cell morphology and cancer progression.
Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion.
Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner.
Induces the formation of apical actin-dependent microvilli.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "PODXL"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1954-sdAb | Recombinant Anti-Human PODXL VHH Single Domain Antibody | IHC, ICC, FC, FA, FUNC | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1053CL | Rabbit Anti-PODXL Recombinant Antibody (TAB-1053CL) | FC, FuncS | Rabbit antibody |
| TAB-1054CL | Mouse Anti-PODXL Recombinant Antibody (TAB-1054CL) | FC, FuncS | Mouse IgG |
| TAB-1053CL-F(E) | Rabbit Anti-PODXL Recombinant Antibody; Fab Fragment (TAB-1053CL-F(E)) | FC | Rabbit Fab |
| TAB-1054CL-F(E) | Mouse Anti-PODXL Recombinant Antibody; Fab Fragment (TAB-1054CL-F(E)) | FC | Mouse Fab |
| TAB-1056CL-F(E) | Mouse Anti-PODXL Recombinant Antibody; Fab Fragment (TAB-1056CL-F(E)) | IHC, FC, WB, ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1056CL | Mouse Anti-PODXL Recombinant Antibody (TAB-1056CL) | ELISA, FC, Cyt, IP, WB, IHC | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2772 | Hi-Affi™ Recombinant Rabbit Anti-PODXL Monoclonal Antibody (DS2772AB) | WB, IHC-P, ICC, IF, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1253-CN | Recombinant Mouse Anti-PODXL Monoclonal Antibody (D0-E8) | WB, IHC | Mouse IgG1 |
| MRO-1254-CN | Recombinant Mouse Anti-PODXL Monoclonal Antibody (2-A4) | IF, IHC | Mouse IgG1 |
| ZG-0167U | Mouse Anti-PODXL Recombinant Antibody (clone 4D2G7) | ELISA, WB, IHC, IP, IF, FC | Mouse IgG2b |
| VS3-QX891 | Mouse Anti-PODXL Recombinant Antibody (clone 632CT5.11.4) | WB, ICC | Mouse IgG1 |
| VS3-XY3471 | Rabbit Anti-PODXL Recombinant Antibody (clone R01-6W4) | WB, IHC-P, ICC, IF, IP, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0611-YC-S(P) | Mouse Anti-PODXL Recombinant Antibody; scFv Fragment (HPAB-M0611-YC-S(P)) | FC, IHC | Mouse scFv |
| HPAB-M0612-YC-S(P) | Human Anti-PODXL Recombinant Antibody; scFv Fragment (HPAB-M0612-YC-S(P)) | FC, IHC | Human scFv |
| HPAB-3334LY-S(P) | Human Anti-PODXL Recombinant Antibody; scFv Fragment (HPAB-3334LY-S(P)) | FC, IHC | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0611-YC-F(E) | Mouse Anti-PODXL Recombinant Antibody; Fab Fragment (HPAB-M0611-YC-F(E)) | FC, IHC | Mouse Fab |
| HPAB-M0612-YC-F(E) | Human Anti-PODXL Recombinant Antibody; Fab Fragment (HPAB-M0612-YC-F(E)) | FC, IHC | Chimeric (Mouse/Human) Fab |
| HPAB-3334LY-F(E) | Human Anti-PODXL Recombinant Antibody; Fab Fragment (HPAB-3334LY-F(E)) | FC, IHC | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC271 | Recombinant Anti-PODXL Vesicular Antibody, EV Displayed (VS-0425-YC271) | Cyt, ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5535 | Anti-Mouse PODXL Immunohistochemistry Kit | IHC | |
| VS-0525-XY5536 | Anti-Rat PODXL Immunohistochemistry Kit | IHC | |
| VS-0525-XY5537 | Anti-Rabbit PODXL Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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