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    Rabbit Anti-PODXL Recombinant Antibody (VS13-YC915) (CAT#: VS13-YC915)

    The Rabbit Anti-PODXL Recombinant Antibody is specific for human PODXL. PODXL encodes a sialomucin family member, part of podocytes in kidneys, binding cytoskeletal elements, expressed in various cells, and involved in differentiation. The anti-PODXL antibody can be used for Immunohistochemistry (1/100-1/200).

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    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoli, plasma membrane, centriolar satellites & vesicles.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2110/118_H1_2_selected.jpg
    Figure 2 IF staining of human cell line A-431
    Figure 2 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to nucleoli, plasma membrane & centriolar satellites.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2110/119_H1_1_blue_red_green.jpg
    Normal Tissue
    Figure 3 Cerebral cortex
    Figure 3 Cerebral cortex
    (Endothelial cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62558/140923_B_9_5.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Bowman's capsule
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Cells in glomeruli
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62558/140923_A_8_5.jpg
    Figure 5 Endometrium
    Figure 5 Endometrium
    (Glandular cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/62558/140923_B_5_3.jpg
    RNA Expression
    Figure 6 RNA cell line category: Cell line enhanced (fHDF/TERT166, NTERA-2, SuSa, TIME, U-251 MG)
    Figure 6 RNA cell line category: Cell line enhanced (fHDF/TERT166, NTERA-2, SuSa, TIME, U-251 MG)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000128567-PODXL

    Specifications

    • Immunogen
    • Recombinant human PODXL.
    • Host Species
    • Rabbit
    • Type
    • Rabbit IgG
    • Specificity
    • Human PODXL
    • Species Reactivity
    • Human
    • Applications
    • IHC-P
    • Conjugate
    • NONE
    • Related Disease
    • Atypical Juvenile Parkinsonism; Young-Onset Parkinson Disease

    Product Property

    • Clonality
    • Monoclonal
    • Purification
    • Affinity Chromatography purified
    • Format
    • Liquid
    • Concentration
    • Please refer to the vial label for the specific concentration.
    • Buffer
    • PBS (pH 7.1) containing 50% Glycerol and 0.5% BSA.
    • Preservative
    • 0.02% Sodium azide
    • Storage
    • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Shipping with ice pack.

    Applications

    • Application Notes
    • Immunohistochemistry (IHC): 1/100-1/200

    Target

    • Alternative Names
    • PC; PDX; PCLP; Gp200; gp135; PCLP-1; PODXL1
    • Long Name
    • podocalyxin like
    • Cellular Localization
    • Apical cell membrane; Cell projection; Lamellipodium
    • Function
    • Involved in the regulation of both adhesion and cell morphology and cancer progression.
      Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion.
      Acts as a pro-adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner.
      Induces the formation of apical actin-dependent microvilli.

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    Secondary Antibody

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    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "PODXL"

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    Please select product type
    Single Domain Antibody Products IgG Antibody Products IgM Antibody Products Mouse Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products Fab Antibody Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    NAB-1954-sdAb Recombinant Anti-Human PODXL VHH Single Domain Antibody IHC, ICC, FC, FA, FUNC Llama VHH

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