Mouse Anti-PPP1CC Recombinant Antibody (VS3-FY2839) (CAT#: VS3-FY2839)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human PPP1CC

• Species Reactivity
• Human

• Applications
• Western Blot, Immunohistochemistry, Flow cytometry, ELISA

• Conjugate
• Unconjugated, FITC

• MW
• The molecular weight of the target protein is approximately 37 kDa.

• Related Disease
• Noonan Syndrome-Like Disorder With Loose Anagen Hair 2 and Rheumatoid Arthritis

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/2000
  Immunohistochemistry: 1/50-1/200
  Flow cytometry: 1/50-1/200
  ELISA: 1/1000-1/10000

• Alternative Names
• PP-1G; PPP1G

• Gene ID
• 5501

• Sequence Similarities
• Belongs to the PPP phosphatase family. PP-1 subfamily.

• Cellular Localization
• Cytoplasm
  Nucleus
  Nucleus, nucleolus
  Nucleus, nucleoplasm
  Nucleus speckle
  Chromosome, centromere, kinetochore
  Cleavage furrow
  Midbody
  Mitochondrion
  Cytoplasm, cytoskeleton, microtubule organizing center

• Post Translation Modifications
• Phosphorylated by NEK2. (P36873-PP1G_HUMAN)
  Ubiquitination at Lys6 and Lys26 (NX_P36873 [NX_P36873-1])
  Modification sites at PhosphoSitePlus (P36873)
  Glycosylation from GlyGen (P36873) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• XP_011536807.1; XP_054228341.1; XP_054228342.1; NP_001231903.1

• Function
• Involved in regulation of ionic conductances and long-term synaptic plasticity.
  May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(²⁺)/calmodulin dependent protein kinase II.
  Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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