Anti-PPP5C (clone W24V73) Recombinant Antibody Coupled Liposome (VS-1024-FY74)
CAT#: VS-1024-FY74
The application of PPP5C antibody-conjugated liposomes in breast cancer provides new possibilities for targeted therapy. These liposomes can facilitate the directional delivery of drugs, enhancing therapeutic efficacy. Studies have shown that functionalized liposomes demonstrate promising prospects in tumor-targeted therapy.
Specifications
- Potential Clinical Applications
- Breast cancer
Product Composition
- Clone
- W24V73
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- The recombinant mouse antibody exhibits a high degree of specificity and binding affinity for human Protein Phosphatase 5, also known as PPP5C. This ability to selectively recognize and bind to PPP5C is essential for various applications in research and therapeutic development.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- PPP5C
- Introduction
- This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress, and elevated levels of this protein may be associated with breast cancer development.
- Alternative Names
- PP5; PPP5; PPT
- Full Name
- Serine/threonine-protein phosphatase 5
- Gene ID
- 5536
- UniProt ID
- P53041
- Sequence Similarities
- Belongs to the PPP phosphatase family.
- Cellular Localization
- Nucleus; Cytoplasm; Cell membrane
- Post Translation Modifications
- Activated by at least two different proteolytic cleavages producing a 56 kDa and a 50 kDa form. ( P53041-PPP5_HUMAN )
Ubiquitination at Lys32 and Lys412 ( NX_P53041 [NX_P53041-1] )
Modification sites at PhosphoSitePlus ( P53041 )
Glycosylation from GlyGen (P53041) 1 site, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001191213.1; NP_006238.1
- Function
- Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT.
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Downloadable Resources
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Datasheet
MSDS
COA
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See other products for "PPP5C"
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
ZG-0386C | Mouse Anti-PPP5C Recombinant Antibody (ZG-0386C) | WB | Mouse IgG |
ZG-0387C | Mouse Anti-PPP5C Recombinant Antibody (ZG-0387C) | WB | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0525-XY5640 | Anti-PPP5C Immunohistochemistry Kit | IHC | |
VS-0525-XY5641 | Anti-Mouse PPP5C Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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