Anti-PRDX2 (clone W24V122) Recombinant Antibody Coupled Liposome (VS-1024-FY124)
CAT#: VS-1024-FY124
The application of liposomes connected with anti-PRDX2 antibodies in glioma represents a new therapeutic strategy. Research has shown that PRDX2 is an antioxidant enzyme that can serve as a therapeutic target and plays a crucial role in cancer progression. By using antibodies targeting PRDX2, the liposomes can more effectively target and kill glioma cells, thereby improving the selectivity and efficiency of the treatment.
More Infomation
Specifications
- Potential Clinical Applications
- Glioma
Product Composition
- Clone
- W24V122
- Antibody Type
- IgG
- Antibody Host
- Mouse
- Antibody Reactivity
- Human
- Antibody Description
- This is a recombinant mouse monoclonal antibody that was designed to specifically target and bind to human Peroxiredoxin 2 (PRDX2). PRDX2 is a crucial antioxidant enzyme that plays a vital role in protecting cells from oxidative stress, and this antibody can be instrumental in various research applications. By utilizing this specific antibody, scientists can effectively study the functions and mechanisms of PRDX2 in human health and disease.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- PRDX2
- Introduction
- This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
- Alternative Names
- PRDX2; NKEFB; TDPX1; Peroxiredoxin-2; Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1
- Full Name
- Peroxiredoxin 2
- Gene ID
- 7001
- UniProt ID
- P32119
- Sequence Similarities
- Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
- Cellular Localization
- Cytoplasm
- Post Translation Modifications
- The enzyme can be inactivated by further oxidation of the cysteine sulfenic acid (C(P)-SOH) to sulphinic acid (C(P)-SO2H) instead of its condensation to a disulfide bond. It can be reactivated by forming a transient disulfide bond with sulfiredoxin SRXN1, which reduces the cysteine sulfinic acid in an ATP- and Mg-dependent manner.
- Protein Refseq
- NP_005800.3
- Function
- Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2.
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Datasheet
MSDS
COA
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See other products for "PRDX2"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3755z | Mouse Anti-PRDX2 Recombinant Antibody (clone 19D8) | WB, IP, IF, ELISA | Mouse IgG2a, κ |
| FAMAB-1519CQ | Mouse Anti-PRDX2 Recombinant Antibody (clone SAIC-34D-11) | Immuno-MRM, WB | Mouse IgG1 |
| FAMAB-1520CQ | Mouse Anti-PRDX2 Recombinant Antibody (clone SAIC-34B-124) | WB, Immuno-MRM, ELISA | Mouse IgG1 |
| VS3-FY1180 | Recombinant Rabbit Anti-PRDX2 Antibody (clone R01-0F0) | WB, IP | Rabbit IgG |
| VS3-FY1181 | Recombinant Rabbit Anti-PRDX2 Antibody (clone R02-1G5) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-1011MZ | Chicken Anti-PRDX2 Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2837 | Hi-Affi™ Recombinant Rabbit Anti-PRDX2 Monoclonal Antibody (DS2837AB) | WB, IHC-P, ICC, IF | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1413 | AbPlus™ Anti-PRDX2 Magnetic Beads (VS-0724-YC1413) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY180 | CytoStream™ Rabbit Anti-PRDX2 Recombinant Antibody (VS-0225-XY180) | FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY5654 | Anti-PRDX2 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5655 | Anti-Mouse PRDX2 Immunohistochemistry Kit | IHC |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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