Human Anti-PRG3 Recombinant Antibody Hexamer (VS-0924-YC145), CDC Enhanced (CAT#: VS-0924-YC145)

The product is a human anti-PRG3 antibody hexamer with enhanced complement-dependent cytotoxicity (CDC) activity. This hexameric IgG1 targets human PRG3 and includes mutations that promote hexamerization. These mutations facilitate optimal C1q binding, thereby enhancing CDC.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Host Species
  • Human
  • Type
  • Antibody hexamer
  • Specificity
  • Human PRG3
  • Species Reactivity
  • Human
  • Molecule Class
  • ~ 900 kDa
  • Applications
  • CDC
  • Conjugate
  • None
  • Related Disease
  • Cancer

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Protein A purified
  • Purity
  • >95% determined as SDS-PAGE and SEC-HPLC
  • Aggregation
  • <5%
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • PRG3; proteoglycan 3; MBP2; MBPH; prepro-MBPH; prepro-major basic protein homolog; eosinophil major basic protein homolog
  • Long Name
  • Proteoglycan 3, Pro Eosinophil Major Basic Protein 2
  • Cellular Localization
  • Cytoplasmic granule
  • Function
  • Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP.
    In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "PRG3"

Select a product category from the dropdown menu below to view related products.
Please select product type
Mouse Antibody Products Hexamer Antibody Products

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for VS-0924-YC145. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Go to compare

    Go to compare