Rabbit Anti-PRKAG1 Recombinant Antibody (VS13-YC930)
CAT#: VS13-YC930
The Rabbit Anti-PRKAG1 Recombinant Antibody is specific for human PRKAG1. PRKAG1 encodes another AMPK regulatory subunit, playing a role in cellular energy sensing and response regulation. The anti-PRKAG1 antibody can be used for Western blot (1/500-1/1000), Immunofluorescence (1/50-1/200), Immunoprecipitation (1/20).
Specifications
- Immunogen
- Recombinant human AMPK gamma 1.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human PRKAG1
- Species Reactivity
- Human
- Applications
- WB, IF, IP
- Conjugate
- NONE
- Related Disease
- Cardiovascular Disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
- Preservative
- 0.01% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/1000
Immunofluorescence (IF): 1/50-1/200
Immunoprecipitation (IP): 1/20
Target
- Alternative Names
- AMPKG
- Gene ID
- 5571
- UniProt ID
- P54619
- Long Name
- protein kinase AMP-activated non-catalytic subunit gamma 1
- Sequence Similarities
- Belongs to the 5'-AMP-activated protein kinase gamma subunit family.
- Cellular Localization
- Cytosol; Nucleoplasm; Nucleus
- Protein Refseq
- NP_001193638.1; NP_001193639.1; NP_002724.1
- Function
- AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "PRKAG1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2849 | Hi-Affi™ Recombinant Rabbit Anti-PRKAG1 Monoclonal Antibody (DS2849AB) | FC, ICC, IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS4-CJ90 | Recombinant Rabbit Anti-PRKAG1 Antibody (clone 5E5) | ELISA, IHC | Rabbit IgG |
| VS3-FY1648 | Rabbit Anti-PRKAG1 Recombinant Antibody (clone R08-7D5) | WB, IP | Rabbit IgG |
| VS3-WK1592 | Mouse Anti-PRKAG1 Recombinant Antibody (clone 5A1) | IHC | Mouse IgG |
| VS3-WK1593 | Mouse Anti-PRKAG1 Recombinant Antibody (clone 5H5) | IHC-P, WB | Mouse IgG |
| VS3-WK1596 | Mouse Anti-PRKAG1 Recombinant Antibody (clone 3G12) | IHC-P, WB | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1746 | Anti-PRKAG1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5676 | Anti-Human PRKAG1 Immunohistochemistry Kit | IHC |
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