Mouse Anti-PSMC3 Recombinant Antibody (clone 1G10B7)
CAT#: VS7-0425-WR705
This product is a mouse IgG1 antibody that binds to human PSMC3. The antibody 1G10B7 recognizes specific amino acid domain of human PSMC3 (AA: 53-152). It can be used for WB, IHC, ICC, and FC assays. It cross reacts with monkey and rat.
Specifications
- Immunogen
- Recombinant human PSMC3 (AA: 53-152) fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human PSMC3
- Species Reactivity
- Human, Monkey, Rat
- Clone
- 1G10B7
- Molecule Class
- 26S Proteasome
- Applications
- WB, IHC, ICC, FC
- Conjugate
- Unconjugated
- Related Disease
- Deafness, cataract, impaired intellectual development, and polyneuropathy (DCIDP)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- 0.05% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry-Paraffin: 1:200 - 1:1000
Immunocytochemistry: 1:200 - 1:1000
Flow Cytometry: 1:200 - 1:400
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- PSMC3; Proteasome 26S Subunit ATPase 3; Proteasome Subunit P50; TBP-1; Human Immunodeficiency Virus Tat Transactivator Binding Protein-1; Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3; Tbp1
- Gene ID
- 5702
- UniProt ID
- P17980
- Long Name
- Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 3
- Cellular Localization
- Cytoplasm; Nucleus; Proteasome
- Post Translation Modifications
- Acetylation; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_002795.2
- Function
- Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Reconstitution Buffer
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "PSMC3"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3087z | Mouse Anti-PSMC3 Recombinant Antibody (clone 30F4) | WB, FC, ICC, IF, IHC | Mouse IgG1 |
| MOB-1705CT | Recombinant Mouse anti-Human PSMC3 Monoclonal antibody (EML2179) | WB | |
| VS7-0425-WR706 | Mouse Anti-PSMC3 Recombinant Antibody (clone 1G10C9) | WB, IHC, ICC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2898 | Hi-Affi™ Recombinant Rabbit Anti-PSMC3 Monoclonal Antibody (DS2898AB) | WB, IHC-P, ICC, IF, FC, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY420 | Mouse Anti-NHP PSMC3 Recombinant Antibody (clone OTI1C10) | WB, IHC, ICC | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1795 | Anti-PSMC3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5791 | Anti-Rat PSMC3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5792 | Anti-Mouse PSMC3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY5790 | Anti-Human PSMC3 Immunohistochemistry Kit | IHC |
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