Rabbit Anti-PTPN11 Recombinant Antibody (clone 7A1) (CAT#: ZG-0535U)

Name: Rabbit Anti-PTPN11 Recombinant Antibody (clone 7A1)
SKU: ZG-0535U
Rating: 5 (1 reviews)

Rabbit Anti-PTPN11 Antibody (clone 7A1) displayed high specificity against the PTPN11 protein of Human.

Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

We require custom production

Tested Data
Gene Expression
Datasheet
MSDS
COA

Figure 1 Rabbit Anti-PTPN11 Antibody (ZG-0535U) in WB

Figure 1 Rabbit Anti-PTPN11 Antibody (ZG-0535U) in WB

Western Blot
Positive WB detected in: Jurkat whole cell lysate, 293 whole cell lysate, MCF-7 whole cell lysate, Hela whole cell lysate, K562 whole cell lysate
All lanes: PTPN11 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 69, 53 kDa
Observed band size: 69 kDa

Subcellular Location

Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm, nucleoli rim, cytosol & actin filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5377/639_H4_1_selected.jpg

Figure 2 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5377/ihc_selected.jpg

Normal Tissue

Figure 3 Cerebral cortex
(Endothelial cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Glial cells
Staining:

High

Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Neuronal cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Neuropil
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5377/18257_B_8_5.jpg

Figure 4 Colon
(Endothelial cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Glandular cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Peripheral nerve/ganglion
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5377/18257_A_8_3.jpg

Figure 5 Kidney
(Cells in glomeruli
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Cells in tubules
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5377/18257_A_7_5.jpg

Figure 6 Testis
(Cells in seminiferous ducts
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Leydig cells
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5377/18257_A_6_6.jpg

Figure 7 Lymph node
(Germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:

High

Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/5377/18257_A_7_8.jpg

RNA Expression

Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000179295-PTPN11

Datasheet

MSDS

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Immunogen
A synthesized peptide derived from human SHP2

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human PTPN11

Species Reactivity
Human

Clone
7A1

Applications
ELISA, WB

Conjugate
Unconjugated

Related Disease
Noonan Syndrome 1 and Juvenile Myelomonocytic Leukemia.

Product Property

Purification
Affinity chromatography purified

Buffer
PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Preservative
0.02% sodium azide

Storage
Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

Application Notes
This antibody has been tested for use in Enzyme-linked Immunosorbent Assay, Western Blot. Specific conditions should be optimized by the end user.
WB:1:500-1:5000

Target

Alternative Names
Tyrosine-protein phosphatase non-receptor type 11; EC 3.1.3.48; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3; PTPN11; PTP2C SHPTP2

Gene ID
5781

UniProt ID
Q06124

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "PTPN11"

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IgG Antibody Products Chicken IgY Antibody Products Rabbit Monoclonal Antibody Products Antibody Magnetic Beads IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry

CAT	Product Name	Application	Type
MOB-1308z	Mouse Anti-PTPN11 Recombinant Antibody (clone 19F6)	ELISA, FC, ICC, IF, IHC, WB	Mouse IgG1
MRO-2375-CN	Recombinant Rabbit Anti-PTPN11 (phosphorylated Tyr542) Monoclonal Antibody (CBACN-661)	WB, IF, IP	Rabbit IgG
VS3-XY1326	Mouse Anti-PTPN11 Recombinant Antibody (clone 6D9F6)	IHC, ICC, FC	Mouse IgG2b
VS3-FY1225	Recombinant Rabbit Anti-PTPN11 Antibody (clone R08-3G2)	WB, IHC-P, IP	Rabbit IgG
VS3-WK2131	Rabbit Anti-PTPN11 (pY542) Recombinant Antibody (clone R03-4L8)	WB, ICC, IF, IP	Rabbit IgG

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