AbPlus™ Anti-PTPRC Magnetic Beads (VS-0724-YC1181)
CAT#: VS-0724-YC1181
The AbPlus Anti-PTPRC Magnetic Beads (VS-0724-YC1181) is an innovative affinity resin which is bound with anti-PTPRC specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PTPRC protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/440/if_selected.jpg
Normal Tissue
Figure 2 Appendix
Lymphoid tissue
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/440/155132_A_3_2.jpg
Normal Tissue
Figure 3 Lymph node
Germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/440/155132_A_8_8.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (Daudi, HEL, HL-60, JURKAT, MOLT-4, THP-1, U-266/70, U-266/84, U-698, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000081237-PTPRC
❮
❯
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-PTPRC specific antibody
- Target
- PTPRC
- Immunogen
- Recombinant human CD45 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.
- Alternative Names
- LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105
- Gene ID
- 5788
- UniProt ID
- P08575
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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|---|---|---|---|
| TAB-240LC | Anti-Human PTPRC Recombinant Antibody (VHE/humV1) | Inhib | Humanized antibody |
| TAB-241LC | Anti-Human PTPRC Recombinant Antibody (VHE/humV2) | Inhib | Humanized antibody |
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| TAB-241LC-F(E) | Anti-Human PTPRC Recombinant Antibody Fab Fragment (VHE/humV2) | ELISA, FC | Humanized antibody |
| TAB-242LC-F(E) | Anti-Human PTPRC Recombinant Antibody Fab Fragment (VHQ/humV1) | ELISA, FC | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-245LC-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (TAB-245LC-F(E)) | ELISA, FC | Human Fab |
| TAB-246LC-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (TAB-246LC-F(E)) | ELISA, FC | Human Fab |
| TAB-247LC-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (TAB-247LC-F(E)) | ELISA, FC | Human Fab |
| TAB-248LC-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (TAB-248LC-F(E)) | ELISA, FC | Human Fab |
| TAB-249LC-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (TAB-249LC-F(E)) | ELISA, FC | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0051MZ | Recombinant Mouse Anti-Human CD45 Antibody (clone A290-11242) | FC, IHC | Mouse antibody |
| FAMAB-1649CQ | Mouse Anti-PTPRC Recombinant Antibody (clone UCH-L1) | IP, WB, FC, IHC | Mouse IgG2a |
| FAMAB-1651CQ | Mouse Anti-PTPRC Recombinant Antibody (clone OX22) | IP, FC, IHC | Mouse IgG1 |
| FAMAB-1652CQ | Mouse Anti-PTPRC Recombinant Antibody (clone OX33) | ICC, IP, FC, IHC | Mouse IgG1 |
| FAMAB-1653CQ | Human Anti-PTPRC Recombinant Antibody (clone OTH-74D4) | FC | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0466MZ | Chicken Anti-PTPRC Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1895CQ | Recombinant Mouse Anti-PTPRC Antibody (HI30) | WB, IP, IHC-Fr, FuncS, ICC, FC, IHC-P, BL | IgG1 |
| NEUT-1896CQ | Recombinant Mouse Anti-Ptprc Antibody (104-2) | FC, IP, BL, IHC-Fr, ICC, IF | IgG2a, κ |
| NEUT-1897CQ | Recombinant Rat Anti-Ptprc Antibody (MAB0822) | BL, FC, IP, WB | IgG2 |
| NEUT-1898CQ | Recombinant Rat Anti-Ptprc Antibody (RA3-6B2) | FC, IHC-Fr, IHC-P, IP, WB, BL | IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2933 | Hi-Affi™ Recombinant Rabbit Anti-PTPRC Monoclonal Antibody (DS2933AB) | IP, WB | IgG |
| MOR-0089-FY | Rabbit Anti-PTPRC Recombinant Antibody (clone AFY0060) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0365-CN-S(P) | Rabbit Anti-PTPRC Recombinant Antibody; scFv Fragment (HPAB-0365-CN-S(P)) | ELISA, FC | Rabbit scFv |
| HPAB-0258-FY-S(P) | Mouse Anti-PTPRC Recombinant Antibody; scFv Fragment (HPAB-0258-FY-S(P)) | ELISA | Mouse scFv |
| HPAB-M0191-YC-S(P) | Human Anti-PTPRC Recombinant Antibody (clone M/YC-14); scFv Fragment | ELISA, WB | Human scFv |
| HPAB-0536-FY-S(P) | Human Anti-PTPRC Recombinant Antibody; scFv Fragment (HPAB-0536-FY-S(P)) | Inhib, FuncS | Human scFv |
| HPAB-0537-FY-S(P) | Mouse Anti-PTPRC Recombinant Antibody; scFv Fragment (HPAB-0537-FY-S(P)) | FC, Block | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0365-CN-F(E) | Rabbit Anti-PTPRC Recombinant Antibody; Fab Fragment (HPAB-0365-CN-F(E)) | ELISA, FC | Rabbit Fab |
| HPAB-0366-CN-F(E) | Human Anti-PTPRC Recombinant Antibody; Fab Fragment (HPAB-0366-CN-F(E)) | ELISA, FC | Humanized Fab |
| FAMAB-0006-CN-F(E) | Mouse Anti-PTPRC Recombinant Antibody (clone LT40); Fab Fragment | FC | Mouse Fab |
| HPAB-M0191-YC-F(E) | Human Anti-PTPRC Recombinant Antibody (clone M/YC-14); Fab Fragment | ELISA, WB | Human Fab |
| HPAB-1058-FY-S(P) | Mouse Anti-PTPRC Recombinant Antibody; scFv Fragment (HPAB-1058-FY-S(P)) | ELISA, Neut | scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-023CN | Mouse Anti-PTPRC Recombinant Antibody (clone ZCH-6-3A4) | FC, IF | Mouse IgG1, κ |
| NS-023CN-F(E) | Mouse Anti-PTPRC Recombinant Antibody (clone ZCH-6-3A4); Fab Fragment | FC, IF | Mouse Fab |
| NS-023CN-S(P) | Mouse Anti-PTPRC Recombinant Antibody (clone ZCH-6-3A4); scFv Fragment | FC, IF | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY220 | AbPlus™ Anti-PTPRC Magnetic Beads (YTH54.12) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY98 | Mouse Anti-NHP PTPRC Recombinant Antibody (clone MEM55) | IHC, FC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY185 | CytoStream™ Rat Anti-PTPRC Recombinant Antibody (clone 30-F11) | FC | Rat IgG2b, kappa |
| VS-0225-XY186 | CytoStream™ Mouse Anti-PTPRC Recombinant Antibody (clone OX-33) | FC | Mouse IgG1, kappa |
| VS13-YC960 | CytoStream™ Rabbit Anti-PTPRC Recombinant Antibody (VS13-YC960) | WB, IHC-P, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY86 | Human Anti-PTPRC (clone VHE-N73D/humV1) scFv-Fc Chimera | IF, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC529 | Recombinant Anti-PTPRC Vesicular Antibody, EV Displayed (VS-0425-YC529) | ELISA, FC, Neut, Cell-uptake |
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