AbPlus™ Anti-PTPRC Magnetic Beads (VS-0724-YC1181) (CAT#: VS-0724-YC1181)

The AbPlus Anti-PTPRC Magnetic Beads (VS-0724-YC1181) is an innovative affinity resin which is bound with anti-PTPRC specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PTPRC protein under native and denaturing conditions.

Specific Inquiry
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magnetic bead
  • Bead Ligand
  • Anti-PTPRC specific antibody
  • Target
  • PTPRC
  • Immunogen
  • Recombinant human CD45 fragment derived from E. coli.
  • Target Species
  • Human
  • Bead Capacity
  • 40 mg/mL
  • Bead size
  • 25 μm
  • Format
  • Suspension
  • Concentration
  • 2 mg/mL
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • 0.1% Sodium azide
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling.
  • Alternative Names
  • LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105

Downloads

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