Rabbit Anti-RAB4A Recombinant Antibody (VS3-CJ770) (CAT#: VS3-CJ770)

• Immunogen
• Recombinant protein

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse, Rat RAB4A

• Species Reactivity
• Human, Mouse, Rat

• Applications
• WB, ICC, IF, IP

• Conjugate
• Unconjugated

• Purification
• Protein A affinity purified

• Purity
• >95% as determined by SDS-PAGE

• Format
• Liquid

• Buffer
• 40% Glycerol, 1% BSA, TBS, pH7.4.

• Preservative
• 0.05% Sodium Azide

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunofluorescence, Immunoprecipitation.

• Alternative Names
• RAB4; HRES1; HRES-1; HRES-1/RAB4

• Gene ID
• 5867

• UniProt ID
• P20338

• Sequence Similarities
• Belongs to the small GTPase superfamily. Rab family.

• Cellular Localization
• Cytoplasm, Endosome, Membrane

• Post Translation Modifications
• Phosphorylated by CDK1 kinase during mitosis.
  Serotonylation of Gln-72 by TGM2 during activation and aggregation of platelets leads to constitutive activation of GTPase activity.

• Protein Refseq
• NP_001258927.1; NP_004569.2

• Function
• Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (PubMed:15907487, PubMed:16034420).
  Involved in protein transport (PubMed:29425100).
  Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (PubMed:29425100).
  Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets (By similarity).

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-057CQ
• Donkey Anti-Rabbit IgG (H&L) Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody