This product is a recombinant human anti-rabies monoclonal antibody (MAb-57) Fab was prepared by cloning the heavy (Fd)- and light-chain domains into the same bacterial expression vector.
Figure 1 Western blot analysis of newly generated anti-rabies virus MAbs.
Rabies virus nucleoprotein (N), glycoprotein (G), phosphoprotein (NS), and matrix protein (M) detected by amido black staining (lane a) and by immunostaining with MAb 52 (lane b), MAb 56 (lane c), MAb 57 (lane d), MAb 58 (lane e), MAb 105 (lane f), and MAb 53 (lane g).
Dietzschold, B. , Gore, M. , Casali, P. , Ueki, Y. , & Koprowski, H. . (1990). Biological characterization of human monoclonal antibodies to rabies virus. Journal of Virology, 64(6), 3087-90.
Figure 2 Specificity of Mab57 for rabies virus or rabies virus G protein as determined by ELISA.
Serial dilutions of MAb-57 were incubated in polystyrene microtiter plates which had been precoated with different antigens.
Cheung, S. C., Dietzschold, B. E. R. N. H. A. R. D., Koprowski, H. I. L. A. R. Y., Notkins, A. L., & Rando, R. F. (1992). A recombinant human Fab expressed in Escherichia coli neutralizes rabies virus. Journal of virology, 66(11), 6714-6720.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0090WJ-F(E) | Human Anti-Rabies Recombinant Antibody (clone Mab-57); Fab Fragment | ELISA, Neut | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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