Recombinant Anti-human RELA Intrabody [(D-Arg)9] (CAT#: IAB-B027(A))

Recombinant anti-RELA intrabody linked to (D-Arg)9 works within cells against RELA, expressed in E. coli cells. This intrabody against p65 subunit can prevent nuclear factor nB (NF-nB) transcriptional activity in glioma cells andbindinhibit the expression of its target genes involved in the invasion and angiogenesis of human gliomas.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • human v-rel avian reticuloendotheliosis viral oncogene homolog A
  • Host Species
  • human
  • Type
  • scFv-(D-Arg)9
  • Cell Penetrating Peptide
  • (D-Arg)9
    It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
  • Species Reactivity
  • human
  • Applications
  • Used for immunoassay techniques such as: Western blot; Coimmunopricipation; Functional studies

Product Property

  • Purity
  • 95% by HPLC
  • Storage
  • ≤6 months at 4°C; ≥6 months at -20°C.

Target

  • Alternative Names
  • RELA; v-rel avian reticuloendotheliosis viral oncogene homolog A; p65; NFKB3; transcription factor p65; NF-kappa-B p65delta3; nuclear factor NF-kappa-B p65 subunit; v-rel reticuloendotheliosis viral oncogene homolog A; nuclear factor of kappa light polype

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "RELA"

Intrabody

CAT Product Name Application Type
IAB-B027(G) Recombinant Anti-human RELA Intrabody [+36 GFP] IF, ELISA, FuncS scFv-(+36GFP)
IAB-B027(T) Recombinant Anti-human RELA Intrabody [Tat] FC, IF, FuncS scFv-Tat

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0722MZ Chicken Anti-Nuclear factor NFκB, p65 subunit (RELA) Polyclonal IgY WB Chicken antibody

Rabbit Monoclonal Antibody

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for IAB-B027(A). Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare