Rat Anti-RNA pol II CTD monomethyl Lys7 Recombinant Antibody (clone 0725W1)
CAT#: VS-0725-FY154
This recombinant antibody, clone 0725W1, is specifically designed to detect RNA pol II CTD monomethyl Lys7. Its immunogen is a peptide featuring dimethyl-lysine 7 within the human RNA Polymerase II C-terminal domain. This antibody is validated for use in Chromatin Immunoprecipitation (ChIP) and Chromatin Immunoprecipitation-Sequencing (ChIP-Seq) applications. The target, RNA Polymerase II, plays a crucial role in transcriptional regulation and chromosome architecture, with the CTD modifications being essential for its activity. This product offers a reliable tool for studying epigenetic regulation and gene expression, providing insights into the complex mechanisms of transcriptional control.
Specifications
- Immunogen
- A peptide that features dimethyl-lysine 7 within the human RNA Polymerase II C-terminal domain (CTD).
- Host Species
- Rat
- Type
- Rat IgG2a
- Specificity
- Human RNA pol II CTD monomethyl Lys7
- Species Reactivity
- Human
- Clone
- 0725W1
- Applications
- Chromatin Immunoprecipitation, Chromatin Immunoprecipitation-Sequencing
- Related Disease
- Cancer
Product Property
- Purification
- Protein G purified
- Molecular Weight
- The molecular weight of the antigen is 240 kDa.
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS, 0.05% BSA
- Preservative
- 0.05% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Chromatin Immunoprecipitation-Sequencing: 10 µg per Chromatin Immunoprecipitation
Immunoprecipitation: 5 µg per Immunoprecipitation
Western Blot: 0.5-2 µg/mL
Target
- Alternative Names
- RNA Polymerase II Carboxy Terminal Domain
- Long Name
- RNA polymerase II C-terminal domain monomethylated at Lysine 7
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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