AbPlus™ Anti-RSPO1 Magnetic Beads (VS-0424-XY228)
CAT#: VS-0424-XY228
The AbPlus Anti-RSPO1 Magnetic Beads (VS-0424-XY228) is an innovative affinity resin which is bound with anti-RSPO1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of RSPO1 protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line THP-1
Immunofluorescent staining of human cell line THP-1 shows localization to vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62923/1944_A10_1_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear Neuronal cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46154/105043_B_9_5.jpg
Normal Tissue
Figure 3 Adrenal gland
Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46154/105043_B_5_5.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46154/105043_A_9_3.jpg
Normal Tissue
Figure 5 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46154/105043_A_9_4.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46154/105043_A_9_5.jpg
Normal Tissue
Figure 7 Testis
Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46154/105043_A_6_6.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (NTERA-2, THP-1)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000169218-RSPO1
❮
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-RSPO1 specific antibody
- Target
- RSPO1
- Immunogen
- Recombinant human RSPO1 protein (aa 31-263)
- Target Species
- Human
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.
- Alternative Names
- RSPO1; R-spondin 1; RSPO; CRISTIN3; R-spondin-1; R-spondin homolog; roof plate-specific spondin-1; anti-RSPO1
- Gene ID
- 284654
- UniProt ID
- Q2MKA7
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "RSPO1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-344CT | Mouse Anti-RSPO1 Recombinant Antibody (TAB-344CT) | WB, ELISA, BL, FC, IP | Mouse IgG |
| TAB-345CT | Mouse Anti-RSPO1 Recombinant Antibody (TAB-345CT) | WB, ELISA, BL, IP | Mouse IgG |
| TAB-344CT-S(P) | Mouse Anti-RSPO1 Recombinant Antibody; scFv Fragment (TAB-344CT-S(P)) | WB, ELISA, BL, FC, IP | Mouse scFv |
| TAB-344CT-F(E) | Mouse Anti-RSPO1 Recombinant Antibody; Fab Fragment (TAB-344CT-F(E)) | WB, ELISA, BL, FC, IP | Mouse Fab |
| TAB-345CT-F(E) | Mouse Anti-RSPO1 Recombinant Antibody; Fab Fragment (TAB-345CT-F(E)) | WB, ELISA, BL, IP | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0830MZ | Recombinant Mouse Anti-Human RSPO1 Antibody (clone 8B7) | ELISA | Mouse antibody |
| HPAB-0020-DJB | Human Anti-RSPO1 Recombinant Antibody (HPAB-0020-DJB) | FC, Block | Humanized IgG |
| HPAB-0021-DJB | Mouse Anti-RSPO1 Recombinant Antibody (HPAB-0021-DJB) | FC, Inhib, FuncS | Mouse IgG |
| ZG-074R | Mouse Anti-RSPO1 Recombinant Antibody (ZG-074R) | WB, ELISA | Mouse IgG |
| VS3-XY1391 | Mouse Anti-RSPO1 Recombinant Antibody (clone 7A6) | ELISA, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1921CQ | Recombinant Rat Anti-Rspo1 Antibody (CBL663) | Neut | IgG2b |
| NEUT-1922CQ | Recombinant Rat Anti-Rspo1 Antibody (CBL882) | Neut | IgG2 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0020-DJB-S(P) | Human Anti-RSPO1 Recombinant Antibody; scFv Fragment (HPAB-0020-DJB-S(P)) | Block | Humanized scFv |
| HPAB-0021-DJB-S(P) | Mouse Anti-RSPO1 Recombinant Antibody; scFv Fragment (HPAB-0021-DJB-S(P)) | Block | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0020-DJB-F(E) | Human Anti-RSPO1 Recombinant Antibody; Fab Fragment (HPAB-0020-DJB-F(E)) | Block | Humanized Fab |
| HPAB-0021-DJB-F(E) | Mouse Anti-RSPO1 Recombinant Antibody; Fab Fragment (HPAB-0021-DJB-F(E)) | Block | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY1974 | Anti-RSPO1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6251 | Anti-Mouse RSPO1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6250 | Anti-Human RSPO1 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC280 | Recombinant Anti-RSPO1 Eliminating Antibody, pH-Sensitive (VS-0625-YC280) | Antigen-Sweeping In Vivo. | Human IgG |
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