Afuco™ Anti-RSV F ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-009) (CAT#: AFC-TAB-009)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human RSV. It is a monoclonal antibody produced by recombinant DNA technology. It is used in the prevention of respiratory syncytial virus (RSV) infections. It is recommended for infants that are high-risk because of prematurity or other medical problems such as congenital heart disease. is a humanized monoclonal antibody (IgG) directed against an epitope in the A antigenic site of the F protein of RSV.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
SDS-PAGE
Figure 1 Afuco Anti-RSV F ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-009) in SDS-PAGE
SDS-PAGE analysis of AFC-TAB-009 in reduced (Lane 1) and non-reduced (Lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result, different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively.
The purity of AFC-TAB-009 was greater than 95% as determined by SDS-PAGE.
SEC-HPLC
Figure 2 Afuco Anti-RSV F ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-009) in HPLC
The purity of AFC-TAB-009 was greater than 94% as determined by SEC-HPLC
Lectin WB
Figure 3 Afuco Anti-RSV F ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-009) in Lectin WB
Western blot analysis of AFC-TAB-009 was performed and fucose was detected by AOL-Biotin and SA-HRP. The result was negative, which indicates that there is almost no fucose produced.
Lane 1: Reducing AFC-TAB-009 (2 μg)
Lane 2: Reducing positive control antibody (2 μg)
Lectin ELISA
Figure 4 Afuco Anti-RSV F ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-009) in Lectin ELISA
Lectin ELISA analysis of AFC-TAB-009 was conducted and fucose was detected using AOL-Biotin and SA-HRP
The result indicates that there is almost no fucose produced.
WB
Figure 5 Afuco Anti-RSV F ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-009) in WB
Western blot analysis of AFC-TAB-009 was performed by loading RSV F.
AFC-TAB-009 incubation concentration: 2 ng/μL.
The secondary antibody: HRP-anti-human IgG
Lane 1: Reducing Antigen (0.1 μg)
Lane 2: Reducing Antigen (0.3 μg)
Lane 3: Reducing Antigen (0.6 μg)
ELISA
Figure 6 Afuco Anti-RSV F ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-009) in ELISA
ELISA analysis of AFC-TAB-009 was performed by coating with RSV F.
The secondary antibody: HRP-anti-human IgG
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Specificity
- Tested positive against native RSV antigen
- Species Reactivity
- RSV
- Applications
- IF, IP, Neut, FuncS, ELISA, FC
- Conjugate
- Unconjugated
- Trade name
- Synagis
- Generic Name
- Palivizumab
- Related Disease
- Respiratory Syncytial Virus (RSV) disease
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- RSV; F; Fusion protein (F); NP_044596.1; UniProt ID: O09720; O09720; Entrez: 1494475; Entrez Gene: 1494475; Gene ID: 1494475;
Related Resources
Please refer to Palivizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Palivizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "RSV F"
Select a product category from the dropdown menu below to view related products.
Please select product type
Humanized Antibody Products
Human Antibody Products
ScFv Antibody Products
Fab Antibody Products
Mouse Antibody Products
IgG Antibody Products
ADCC Enhanced Antibody Products
MHC Tetramer Products for Virology
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-009 | Human Anti-RSV Recombinant Antibody (TAB-009) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| TAB-709 | Anti-RSV glycoprotein F Recombinant Antibody (TAB-709) | IF, IP, Neut, FuncS, ELISA, FC, WB | IgG1 - kappa |
| MRO-1209LC | Anti-HRSV F Recombinant Antibody (MEDI-493) | ELISA, Neut, PK | Humanized antibody |
| MRO-1209LC-S(P) | Anti-HRSV F Recombinant Antibody scFv Fragment (MEDI-493) | ELISA | Humanized antibody |
| MRO-1209LC-F(E) | Anti-HRSV F Recombinant Antibody Fab Fragment (MEDI-493) | ELISA | Humanized antibody |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-TAB-009. Click the button above to contact us or submit your feedback about this product.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# AFC-TAB-009, RRID: AB_3111281)
Copy citation
Popular products with customers
-2.png)
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
-2.png)
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
Application: WB, ELISA, FuncS
Application: ELISA, FuncS, IHC, IF, FC, ADCC
Application: WB, ELISA, IF, FuncS, Apop, BA
Application: ELISA, IHC, FC, IP, IF, BL
Application: ELISA, WB, FC, IHC, IP
Application: ELISA, IHC, IF, IP, FC, FuncS
Application: ELISA, Inhib, FuncS
Application: WB, FC, IF, Inhib, ELISA, IHC
-3.jpg)
Application: IB, FC, ELISA, FuncS
Application: ELISA, Inhib, FuncS
Application: ELISA, Inhib, FuncS
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
