Afuco™ Anti-S. aureus ClfA ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-029)
CAT#: AFC-TAB-029
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human S. aureus. It is a humanized monoclonal antibody for the treatment of severe infections with Staphylococcus aureus. Possible indications include the treatment of S. aureus in patient with cystic fibrosis and of methicillin-resistant S. aureus.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Specificity
- Tested positive against native S. aureus antigen.
- Species Reactivity
- S. aureus
- Applications
- IP, IF, FuncS, FC, Neut, ELISA
- Conjugate
- Unconjugated
- Trade name
- Aurexis
- Generic Name
- Tefibazumab
- Related Disease
- Staphylococcal infections
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- S. aureus; Staphylococcus aureus; ClfA protein; NC_002952.2
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Biosimilar Overview
Please refer to Tefibazumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tefibazumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Tefibazumab"
DrugMonitor™ Anti-Tefibazumab Antibody (VS-1224-YC1168)Tefibazumab is a humanized monoclonal antibody that specifically recognizes ClfA, used for treating severe infections caused by Staphylococcus aureus. The DrugMonitor™ Anti-Tefibazumab Antibody (VS-1224-YC1168) is an anti-drug antibody (ADA) against Tefibazumab. This drug-based antibody is raised in mice immunized with the Tefibazumab. The anti-Tefibazumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Tefibazumab in samples.
See other products for "S. aureus ClfA"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2210-sdAb | Recombinant Anti-S. aureus ClfA VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-029 | Anti-S. Aureus Recombinant Antibody (TAB-029) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
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