Recombinant Alpaca Anti-S. flexneri ipaD Single Domain Antibody (JMK-H2) (CAT#: PABC-552)

This product is a recombinant Alpaca antibody that can recognize S. flexneri ipaD.


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Neut

Figure 1 Alpaca Anti-S. flexneri ipaD Single Domain Antibody (JMK-H2) in Neut.

Figure 1 Alpaca Anti-S. flexneri ipaD Single Domain Antibody (JMK-H2) in Neut.

Inhibition of Shigella-mediated Hemolytic Activity. The ability of each VHH to prevent hemoglobin release caused by contact-mediated lysis was evaluated and plotted relative to a wild-type Shigella flexneri control (set at 100%). Data are representative of at least six independent tests for each VHH. Relative hemolysis for the evaluated hetero-dimers is plotted on the far right.

Barta, M. L. , Shearer, J. P. , Arizmendi, O. , Tremblay, J. M. , Mehzabeen, N. , & Zheng, Q. , et al. (2017). Single-domain antibodies pinpoint potential targets within shigella invasion plasmid antigen d of the needle tip complex for inhibition of type iii secretion. Journal of Biological Chemistry, jbc.M117.802231.


Specifications

  • Host Species
  • Alpaca
  • Type
  • Alpaca VHH
  • Specificity
  • S. flexneri ipaD
  • Species Reactivity
  • S. flexneri
  • Clone
  • JMK-H2
  • Applications
  • ELISA

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store at -20°C for long-term storage. Avoid freeze/thaw cycles.

Target

  • Alternative Names
  • ipaD; Invasin IpaD; S. flexneri ipaD; Shigella flexneri

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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