Human Anti-S1PR3 Recombinant Antibody (clone AS55)

CAT#: VS-0624-FY30

This is a recombinant human antibody that binds to human S1PR3. It recognizes the extracellular domain of S1PR3, including the N-terminal loop. The antibody was generated by mice immunized with liposomal S1PR3.

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (AF22, ASC diff, ASC TERT1)

Specifications

  • Immunogen
  • The mice were immunized with liposomal S1PR3.
  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • Human S1PR3
  • Species Reactivity
  • Human
  • Clone
  • AS55
  • Applications
  • ELISA
  • Related Disease
  • Dermatitis, Atopic, 7 and Pulmonary Edema

Product Property

  • Clonality
  • Monoclonal Antibody
  • Purification
  • Protein A purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS, pH 7.4
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Sphingosine-1-Phosphate Receptor 3; Endothelial Differentiation, Sphingolipid G-Protein-Coupled Receptor, 3; Endothelial Differentiation G-Protein Coupled Receptor 3; Sphingosine 1-Phosphate Receptor Edg-3; S1P Receptor Edg-3; S1P Receptor 3; EDG3
  • Long Name
  • Sphingosine-1-Phosphate Receptor 3
  • Sequence Similarities
  • Belongs to the G-protein coupled receptor 1 family.
  • Cellular Localization
  • Cell membrane
  • Post Translation Modifications
  • Glycosylation at Asn15 (NX_Q99500 [NX_Q99500-1])
    Modification sites at PhosphoSitePlus (Q99500)
    Glycosylation from GlyGen (Q99500) 2 sites, 1 O-linked glycan (1 site)
  • Function
  • Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P).
    S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.
    When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

MSDS

COA

Certificate of Analysis Lookup

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Secondary Antibody

Isotype Control

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