Human Anti-S1PR3 Recombinant Antibody (clone AS55) (CAT#: VS-0624-FY30)
This is a recombinant human antibody that binds to human S1PR3. It recognizes the extracellular domain of S1PR3, including the N-terminal loop. The antibody was generated by mice immunized with liposomal S1PR3.
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RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (AF22, ASC diff, ASC TERT1)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213694-S1PR3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000213694-S1PR3
Specifications
- Immunogen
- The mice were immunized with liposomal S1PR3.
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human S1PR3
- Species Reactivity
- Human
- Clone
- AS55
- Applications
- ELISA
- Related Disease
- Dermatitis, Atopic, 7 and Pulmonary Edema
Product Property
- Clonality
- Monoclonal Antibody
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Sphingosine-1-Phosphate Receptor 3; Endothelial Differentiation, Sphingolipid G-Protein-Coupled Receptor, 3; Endothelial Differentiation G-Protein Coupled Receptor 3; Sphingosine 1-Phosphate Receptor Edg-3; S1P Receptor Edg-3; S1P Receptor 3; EDG3
- Gene ID
- 1903
- UniProt ID
- Q99500
- Long Name
- Sphingosine-1-Phosphate Receptor 3
- Sequence Similarities
- Belongs to the G-protein coupled receptor 1 family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn15 (NX_Q99500 [NX_Q99500-1])
Modification sites at PhosphoSitePlus (Q99500)
Glycosylation from GlyGen (Q99500) 2 sites, 1 O-linked glycan (1 site)
- Protein Refseq
- NP_001382777.1; NP_005217.2
- Function
- Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P).
S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues.
When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1777MZ | Recombinant Mouse Anti-Human S1PR3 Antibody (clone BT72) | WB | Mouse antibody |
| HPAB-0437-WJ | Mouse Anti-S1PR3 Recombinant Antibody (clone 7H9F11) | ELISA, ICC | Mouse IgG |
| VS13-YC1032 | Rabbit Anti-S1PR3 Recombinant Antibody (VS13-YC1032) | WB | Rabbit IgG |
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