AbPlus™ Anti-SAE1 Magnetic Beads (VS-0724-YC1142) (CAT#: VS-0724-YC1142)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-SAE1 specific antibody

• Target
• SAE1

• Immunogen
• Recombinant human SAE1, aa 1-346.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]

• Alternative Names
• SUMO1 Activating Enzyme Subunit 1; Ubiquitin-Like 1-Activating Enzyme E1A; UBLE1A; AOS1; SUA1; Ubiquitin-Like Protein SUMO-1 Activating Enzyme; SUMO-1 Activating Enzyme E1 N Subunit;

• Gene ID
• 10055

• UniProt ID
• Q9UBE0

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