Human Anti-SARS-CoV-2 S protein Recombinant Antibody (clone 11-11) (CAT#: VS-0623-WK37)
The antibody clone 11-11 was produced by immunizing with recombinant SARS-CoV-2 S protein. The antibody recognized epitopes within the receptor binding domain (RBD) and inhibited the binding of soluble human angiotensin converting enzyme 2 (ACE2) receptor to the S protein. It can be used for detection of SARS-CoV-2 S protein in ELISA and SPR assays.
Specific Inquiry
ELISA
Figure 1 10-28, 10-40, and 11-11 were tested for binding to SARS CoV-2 D614G, B.1.351, SARS-CoV, as well as the RBD of D614G.
The horizontal dashed lines indicate OD=1.2, the half-maximal binding value.
Inhib
Figure 2 Inhibition of ACE2 binding to SARSCoV-2 D614G, B.1.351, and SARS-CoV S proteins was tested for 10-28, 10-40, and 11-11.
Neut
Figure 3 Neutralization curves of selected mAbs against VSV pseudotypes with D614G (WT) and B.1.1.529.1 S proteins are shown.
The dotted horizontal line at 50% indicates IC50 values.
FC
Figure 4 Binding of mAbs to S proteins expressed on the surface of transfected cells was measured by flow cytometry.
Specifications
- Immunogen
- Recombinant SARS-CoV-2 S protein
- Host Species
- Human
- Type
- Human IgG
- Specificity
- SARS-CoV-2 S protein
- Species Reactivity
- SARS-CoV-2 (D614G and B.1.351 variant)
- Clone
- 11-11
- Applications
- ELISA, SPR, Neut, Inhib, FC
- Conjugate
- Unconjugated
- Related Disease
- COVID-19
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No Preservative
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0623-WK35 | Human Anti-SARS-CoV-2 S protein Recombinant Antibody (clone 10-40) | ELISA, SPR, Neut, Inhib, FC, FuncS | Human IgG |
| VS-0623-WK36 | Human Anti-SARS-CoV-2 S protein Recombinant Antibody (clone 10-28) | ELISA, SPR, Neut, Inhib | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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