Human Anti-SARS-CoV-2 S2 Recombinant Antibody (clone CC40.8) (CAT#: VS-0723-CJ14)

This human anti-SARS-CoV-2 S2 antibody CC40.8 is a product that recognizes SARS-CoV-2 S2. This antibody CC40.8 targets the conserved S2 stem-helix region of the coronavirus spike fusion machinery and exhibits broad reactivity with human beta-coronaviruses (β-CoVs). This antibody has been tested for use in enzyme-linked immunosorbent assay, immunofluorescence and inhibition assays.


Specific Inquiry
  • Size:
  • Conjugation:
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  • Purity:
  • Fc Engineering:
  • Datasheet
  • MSDS
  • COA

Specifications

  • Host Species
  • Human
  • Type
  • Human IgG
  • Specificity
  • SARS-CoV-2 S2
  • Species Reactivity
  • SARS-CoV-2
  • Clone
  • CC40.8
  • Applications
  • ELISA, IF, Inhib
  • Conjugate
  • Unconjugated
  • Related Disease
  • COVID-19

Product Property

  • Purification
  • Protein A purified
  • Purity
  • >95%
  • Buffer
  • PBS
  • Storage
  • Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • CC40.8 can effectively neutralize clade 1b and clade 1a ACE2 receptor-utilizing sarbecoviruses. CC40.8 can prevent cell-cell fusion of HeLa cells expressing SARS-CoV-2 spike protein with HeLa cells expressing the hACE2 receptor. Pseudotyped viral neutralization assay was performed, 25 μl of virus was mixed with 25 μl of three-fold serially diluted this antibody (starting concentration of 300 μg/ml). Binding of this antibody to various human coronavirus spike proteins expressed on the surface of HEK293T cells was determined by flow cytometry.

Target

  • Alternative Names
  • SARS-CoV-2 S2

Recommended Products

Recommended Dilution Buffer

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "SARS-CoV-2 S2"

Human Antibody

CAT Product Name Application Type
VS3-WK1248 Human Anti-SARS-CoV-2 S2 Recombinant Antibody (clone S2a) ELISA Human IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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