CytoStream™ Rabbit Anti-SCNN1A Polyclonal Antibody (VS13-YC1043) (CAT#: VS13-YC1043)
The CytoStream™ Rabbit Anti-SCNN1A Polyclonal Antibody is specific for human, mouse and rat SCNN1A. SCNN1A encodes a sodium channel subunit vital for epithelial fluid and electrolyte transport, with mutations leading to pseudohypoaldosteronism. The anti-SCNN1A antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (5 μg per 1x 10⁶ cells).
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Normal Tissue
RNA Expression
Figure 1 Colon
(Enterocytes Staining: Low Intensity: Moderate Quantity: <25% Enterocytes - Microvilli Staining: High Intensity: Strong Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12743/33366_A_9_3.jpg
(Enterocytes Staining: Low Intensity: Moderate Quantity: <25% Enterocytes - Microvilli Staining: High Intensity: Strong Mucosal lymphoid cells Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12743/33366_A_9_3.jpg
Figure 2 Gallbladder
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12743/33366_A_5_4.jpg
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12743/33366_A_5_4.jpg
Figure 3 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12743/33366_A_6_6.jpg
(Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Sertoli cells Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12743/33366_A_6_6.jpg
Figure 4 RNA cell line category: Cell line enhanced (CAPAN-2, HBEC3-KT, hTCEpi, RPTEC TERT1, RT4, SK-BR-3)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111319-SCNN1A
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000111319-SCNN1A
Specifications
- Immunogen
- Recombinant human Alpha-ENaC, aa 201-300, conjugated with KLH.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat SCNN1A
- Species Reactivity
- Human, Mouse, Rat, Dog (Predicted), Pig (Predicted), Cow (Predicted), Horse (Predicted), Sheep (Predicted)
- Applications
- WB, ELISA, IHC-P, IHC-Fr, FC, IF
- Conjugate
- NONE
- Related Disease
- Pseudohypoaldosteronism type 1 (PHA1)
Product Property
- Clonality
- Polyclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01× TBS (pH 7.4) containing 50% Glycerol and 1% BSA.
- Preservative
- 0.03% Proclin 300
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/500-1/2000
ELISA: 1/5000-1/10000
Immunohistochemistry-paraffin (IHC-P): 1/100-1/500
Immunohistochemistry-frozen (IHC-Fr): 1/100-1/500
Flow cytometry (FC): 5 μg per 1x 10⁶ cells
Immunofluorescence (IF): 1/100-1/500
Target
- Alternative Names
- Sodium Channel Epithelial 1 Alpha Subunit; Sodium Channel, Non Voltage Gated 1 Alpha Subunit; Nonvoltage-Gated Sodium Channel 1 Subunit Alpha; Sodium Channel, Non-Voltage-Gated 1 Alpha; Sodium Channel, Nonvoltage-Gated 1 Alpha; Epithelial Na(+) Channel Subunit Alpha; Alpha-ENaC; Alpha-NaCH; ENaCa; SCNN1;
- Gene ID
- 6337
- UniProt ID
- P37088
- Long Name
- Sodium Channel Epithelial 1 Alpha Subunit
- Cellular Localization
- Apical cell membrane
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody Products
Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-414CT | Human Anti-SCNN1A Recombinant Antibody (TAB-414CT) | WB, ELISA, IHC, FC | Human IgG |
| TAB-414CT-S(P) | Human Anti-SCNN1A Recombinant Antibody; scFv Fragment (TAB-414CT-S(P)) | WB, ELISA, IHC, FC | Human scFv |
| TAB-414CT-F(E) | Human Anti-SCNN1A Recombinant Antibody; Fab Fragment (TAB-414CT-F(E)) | WB, ELISA, IHC, FC | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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