SmartAb™ Recombinant Anti-SEB pH-dependent Antibody (Clone 3E2)
CAT#: VS-0825-YC12
This is a pH-dependent antibody that exhibits high-affinity binding at pH 7.4 and rapid dissociation at pH 6.0. A higher mean fluorescence intensity (MFI) at pH 7.4 compared to pH 6.0 indicated stronger binding to SEB at the higher pH. The antibody inhibits SEB's activity by interfering with its interaction with MHC II on antigen-presenting cells. Staphylococcus aureus enterotoxin B (SEB) is a potent superantigen produced by the bacterium S. aureus that causes food poisoning and can lead to toxic shock syndrome. It triggers a massive, non-specific activation of T-cells, which leads to an overproduction of cytokines and a severe inflammatory response.
Specifications
- Host Species
- Human
- Type
- Human IgG1 kappa
- Specificity
- S. aureus enterotoxin B (SEB)
- Species Reactivity
- S. aureus
- Clone
- 3E2
- Applications
- WB, ELISA, Neut
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95%, determined by SDS-PAGE and SEC-HPLC
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- For short-term storage, keep it at 4°C for up to two weeks. For long-term storage, divide the solution into aliquots and freeze them at -20°C or below.
Target
- Alternative Names
- Enterotoxin B; SEB; Staphylococcal enterotoxin B; enterotoxin type B
- Long Name
- Staphylococcal enterotoxin B
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone 3E2"
- CAT
- Product Name
See other products for "SEB"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-895 | Recombinant Anti-SEB Antibody | ELISA, IF, FuncS | IgG |
| MHH-895 | Recombinant Human Anti-SEB Antibody | WB, Dot, FuncS | IgG |
| MOB-0872CT | Recombinant Mouse anti-Staphylococcus aureus seb Monoclonal antibody (T333) | sELISA | |
| HPAB-0915-FY | Recombinant Anti-SEB Antibody (FMU-SEB-No.1) | N, I, E | |
| PABS-0023 | Mouse Anti-Staphylococcal enterotoxin B (SEB) Recombinant Antibody (Clone 4PCL2) | ELISA, SPR, FuncS | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-895-F(E) | Recombinant Anti-SEB Antibody Fab Fragment | ELISA, FacS, FuncS | Fab |
| MHH-895-F(E) | Recombinant Human Anti-SEB Antibody Fab Fragment | WB, IP, FuncS | Fab |
| FAMAB-0254-CN-F(E) | Recombinant Mouse Anti-SEB Antibody Fab Fragment (2F6D9G2) | WB, ELISA | Mouse Fab |
| HPAB-0090-FY-F(E) | Recombinant Mouse Anti-SEB Antibody Fab Fragment (FMU-SEB-No.2) | E | |
| HPAB-0915-FY-S(P) | Recombinant Anti-SEB Antibody Fab Fragment (FMU-SEB-No.1) | N, I, E |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-895-S(P) | Recombinant Anti-SEB Antibody scFv Fragment | ELISA, WB, FC, FuncS | scFv |
| MHH-895-S(P) | Recombinant Human Anti-SEB Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| PSBL-336 | Recombinant Human Anti-Staphylococcal enterotoxin B (SEB) Antibody scFv Fragment (3E2) | WB, ELISA, Neut, FuncS | scFv |
| FAMAB-0254-CN-S(P) | Recombinant Mouse Anti-SEB Antibody scFv Fragment (2F6D9G2) | WB, ELISA | Mouse scFv |
| HPAB-0090-FY-S(P) | Recombinant Mouse Anti-SEB Antibody scFv Fragment (FMU-SEB-No.2) | E |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-029 | Recombinant Anti-Staphylococcal SEB VHH Single Domain Antibody (PNBL-029) | SPR | Llama VHH |
| PNBL-094 | Recombinant Anti-Staphylococcal enterotoxin B (SEB) VHH Single Domain Antibody (PNBL-094) | WB, FuncS | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY90 | Human Anti-SEB (clone SEB3-2-7) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC301 | SmartAb™ Recombinant Anti-SEB pH-dependent Antibody (Clone 2F6D9G2) | WB, ELISA | Mouse IgG1 |
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