The participation of L-selectin in leukocyte recruitment during inflammation has suggested the use of L-selectin inhibitors as potential anti-inflammatory therapeutics. Blocking monoclonal antibodies could serve as such therapeutic agents. HuDREG-55 block L-selectin-dependent adhesion of human lymphocytes to high endothelial venules in frozen sections of lymph nodes. In addition, HuDREG-55 are inhibitory in a novel L-selectin-dependent adhesion assay.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
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NAB-2242-VHH | Recombinant Anti-Human SELL VHH Single Domain Antibody | Neut, ChiP, IP, FUNC | Llama VHH |
CAT | Product Name | Application | Type |
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TAB-720 | Anti-SELL/CD62L Recombinant Antibody (Aselizumab) | FC, IP, ELISA, Neut, FuncS, IF, WB | IgG4 |
TAB-0710CL | Human Anti-SELL Recombinant Antibody (TAB-0710CL) | ELISA | Humanized antibody |
TAB-0710CL-S(P) | Human Anti-SELL Recombinant Antibody; scFv Fragment (TAB-0710CL-S(P)) | ELISA | Humanized scFv |
TAB-0710CL-F(E) | Human Anti-SELL Recombinant Antibody; Fab Fragment (TAB-0710CL-F(E)) | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
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MOB-1371MZ | Recombinant Mouse Anti-Rat SELL Antibody (clone NSD PY-96), Biotin-Conjugated | ELISA, FC | Mouse antibody |
FAMAB-0208YC | Mouse Anti-SELL Recombinant Antibody (clone DREG-55) | FC, FuncS | Mouse IgG |
FAMAB-0209YC | Mouse Anti-SELL Recombinant Antibody (clone DREG-200) | FC, FuncS | Mouse IgG |
ZG-0698F | Mouse Anti-SELL Recombinant Antibody (clone 1H3) | FC | Mouse IgG2a |
VS3-WK1492 | Mouse Anti-SELL Recombinant Antibody (clone E56) | FC, IF | Mouse IgG1 |
CAT | Product Name | Application | Type |
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NEUT-1931CQ | Recombinant Mouse Anti-SELL Antibody (DREG-56) | FC, WB, BL | IgG1, κ |
NEUT-1932CQ | Recombinant Rat Anti-SELL Antibody (MEL-14) | ICC, IHC-Fr, IHC-P, IP, BL, FC | IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4409 | Hi-Affi™ Recombinant Rabbit Anti-SELL Monoclonal Antibody (SI501DS) | FC | IgG |
MOR-4410 | Hi-Affi™ Recombinant Rabbit Anti-SELL Monoclonal Antibody (SI502DS) | FC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0104-LS-S(P) | Mouse Anti-SELL Recombinant Antibody; scFv Fragment (HPAB-0104-LS-S(P)) | ELISA | Mouse scFv |
FAMAB-0208-YC-S(P) | Mouse Anti-SELL Recombinant Antibody (clone DREG-55); scFv Fragment | FC, FuncS | Mouse scFv |
FAMAB-0209-YC-S(P) | Mouse Anti-SELL Recombinant Antibody (clone DREG-200); scFv Fragment | FC, FuncS | Mouse scFv |
FAMAB-0210-YC-S(P) | Human Anti-SELL Recombinant Antibody (clone HuDREG-55); scFv Fragment | FC, FuncS | Humanized scFv |
FAMAB-0211-YC-S(P) | Human Anti-SELL Recombinant Antibody (clone HuDREG-200); scFv Fragment | FC, FuncS | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0104-LS-F(E) | Human Anti-SELL Recombinant Antibody; Fab Fragment (HPAB-0104-LS-F(E)) | ELISA | Human Fab |
FAMAB-0208-YC-F(E) | Mouse Anti-SELL Recombinant Antibody (clone DREG-55); Fab Fragment | FC, FuncS | Mouse Fab |
FAMAB-0209-YC-F(E) | Mouse Anti-SELL Recombinant Antibody (clone DREG-200); Fab Fragment | FC, FuncS | Mouse Fab |
FAMAB-0211-YC-F(E) | Human Anti-SELL Recombinant Antibody (clone HuDREG-200); Fab Fragment | FC, FuncS | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-720 | Afuco™ Anti-SELL ADCC Recombinant Antibody (Aselizumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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