Mouse Anti-SELL Recombinant Antibody (clone DREG-200) (CAT#: FAMAB-0209YC)
The participation of L-selectin in leukocyte recruitment during inflammation has suggested the use of L-selectin inhibitors as potential anti-inflammatory therapeutics. Blocking monoclonal antibodies could serve as such therapeutic agents. The mouse monoclonal antibody, DREG-200, that block human L-selectin.
Specific Inquiry
RIA
Figure 1 Competition of radiolabeled antibodies with mouse and humanized DREG-55 (A) or DREG-200 (B).
Each point shows the average of duplicate samples.
FACS
Figure 2 Binding of polymerized liposomes containing sialyl Lewis X to peripheral blood lymphocytes and neutrophils in the presence of anti-L-selectin antibodies.
Following a 1h incubation and washing, cells were evaluated by flow cytometry with a Becton Dickinson FACScan using FL3.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human SELL
- Species Reactivity
- Human, Chimpanzee
- Clone
- DREG-200
- Applications
- FC, FuncS
- Related Disease
- Inflammatory
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- TQ1; LAM1; LEU8; LNHR; LSEL; CD62L; LYAM1; PLNHR; LECAM1
- Gene ID
- 6402
- UniProt ID
- P14151
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-2242-VHH | Recombinant Anti-Human SELL VHH Single Domain Antibody | Neut, ChiP, IP, FUNC | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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