Rabbit Anti-SERPINA3 Recombinant Antibody (VS13-YC1048) (CAT#: VS13-YC1048)
The Rabbit Anti-SERPINA3 Recombinant Antibody is specific for human SERPINA3. SERPINA3 encodes a plasma protease inhibitor affecting protease targeting, with variations linked to diseases like Alzheimer's. The anti-SERPINA3 antibody can be used for Immunohistochemistry (1/100-1/200).
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Normal Tissue
RNA Expression
Figure 1 IHC staining of human cervix, uterine
(Immunohistochemical staining of human cervix, uterine shows moderate cytoplasmic staining in glandular cells and secreted positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16647/166236_B_7_3_selected.jpg
(Immunohistochemical staining of human cervix, uterine shows moderate cytoplasmic staining in glandular cells and secreted positivity.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/16647/166236_B_7_3_selected.jpg
Figure 2 Liver
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2560/166232_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2560/166232_A_7_4.jpg
Figure 3 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2560/166232_A_4_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2560/166232_A_4_6.jpg
Figure 4 Cervix
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2560/166232_B_7_3.jpg
(Glandular cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2560/166232_B_7_3.jpg
Figure 5 RNA cell line category: Cell line enriched (Hep G2)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196136-SERPINA3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000196136-SERPINA3
Specifications
- Immunogen
- Recombinant human AACT.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human SERPINA3
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Parkinson disease and chronic obstructive pulmonary disease
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.4) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- Serpin Family A Member 3; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3; Cell Growth-Inhibiting Gene 24/25 Protein; Alpha-1-Antichymotrypsin; Serpin A3; AACT; ACT;
- Gene ID
- 12
- UniProt ID
- P01011
- Long Name
- Serpin Family A Member 3
- Cellular Localization
- Secreted
- Protein Refseq
- NP_001371601.1; NP_001076.2
- Function
- Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "SERPINA3"
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IgG Antibody Products
Rabbit Monoclonal Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1778z | Mouse Anti-SERPINA3 Recombinant Antibody (clone 28F4) | WB, FC, ICC, IHC | Mouse IgG1 |
| MOB-0507MZ | Recombinant Mouse Anti-Human SERPINA3 Antibody (clone 71A1) | IHC-P, WB, sELISA | Mouse antibody |
| MRO-0060-CN | Recombinant Rabbit Anti-SERPINA3 Monoclonal Antibody (JM83-29) | WB, IHC, IP | Rabbit IgG |
| VS3-WK132 | Mouse Anti-SERPINA3 Recombinant Antibody (clone G3-C11) | WB, IHC, FC | Mouse IgG1 |
| VS3-XY3499 | Rabbit Anti-SERPINA3 Recombinant Antibody (clone R03-4U6) | WB, IHC-P, ICC, IF, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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