Mouse Anti-SERPINC1 Recombinant Antibody (VS3-FY2869)
CAT#: VS3-FY2869
The anti-SERPINC1 antibody is a mouse recombinant monoclonal antibody that was direct against the human, rat SERPINC1 protein. The calculated molecular weight of the protein is about 52.6 kDa. The monoclonal antibody can be used in the area of Antithrombin Iii Deficiency and Thrombosis.
Gene Expression
Normal Tissue
Figure 1 Liver
Hepatocytes
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16790/39120_A_9_4.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enriched (Hep G2)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117601-SERPINC1
❮
❯
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human, Rat SERPINC1
- Species Reactivity
- Human, Rat
- Applications
- Western Blot
- Conjugate
- Unconjugated, FITC
- MW
- The molecular weight of the target protein is approximately 52.6 kDa.
- Related Disease
- Antithrombin Iii Deficiency and Thrombosis
Product Property
- Clonality
- Monoclonal Antibody
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/100-1/1600
Target
- Alternative Names
- Serpin Family C Member 1; Serine (Or Cysteine) Proteinase Inhibitor, Clade C (Antithrombin), Member 1; Serpin Peptidase Inhibitor, Clade C (Antithrombin), Member 1; ATIII; AT3; Coding Sequence Signal Peptide Antithrombin Part 1; Serpin Peptidase Inhibitor Clade C Member 1; Signal Peptide Antithrombin Part 1
- Gene ID
- 462
- UniProt ID
- P01008
- Sequence Similarities
- Belongs to the serpin family.
- Cellular Localization
- Secreted, extracellular space
- Post Translation Modifications
- Phosphorylated by FAM20C in the extracellular medium. (P01008-ANT3_HUMAN)
Glycosylation at Asn128, Asn167, Asn187, and Asn224 (NX_P01008 [NX_P01008-1])
Modification sites at PhosphoSitePlus (P01008)
Glycosylation from GlyConnect ANT3_HUMAN (766)
Glycosylation from GlyGen (P01008) 7 sites, 25 N-linked glycans (4 sites), 2 O-linked glycans (1 site)
- Protein Refseq
- NP_001351981.1; NP_001373231.1; NP_001373232.1; NP_001373233.1
- Function
- Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade (PubMed:15853774, 15140129).
AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa (PubMed:15140129).
Its inhibitory activity is greatly enhanced in the presence of heparin.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "SERPINC1"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1168z | Mouse Anti-SERPINC1 Recombinant Antibody (clone 22B11) | ELISA, WB, FuncS | Mouse IgG1 |
| MOB-0511MZ | Recombinant Mouse Anti-Human SERPINC1 Antibody | ELISA, WB | Mouse antibody |
| MRO-2181-CN | Rabbit Anti-SERPINC1 Polyclonal Antibody (MRO-2181-CN) | WB, IF, IHC, FC | Rabbit IgG |
| VS3-XY1416 | Mouse Anti-SERPINC1 Recombinant Antibody (clone 435CT4.7.4) | WB | Mouse IgG1 |
| VS13-YC1049 | Rabbit Anti-SERPINC1 Recombinant Antibody (VS13-YC1049) | WB, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1943CQ | Recombinant Mouse Anti-SERPINC1 Antibody (BDI205) | WB, BL, ELISA, Dot, ICC, IF, IHC-P, IP | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3222 | Hi-Affi™ Recombinant Rabbit Anti-SERPINC1 Monoclonal Antibody (DS3222AB) | WB, ICC | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2036 | Anti-SERPINC1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6489 | Anti-Human SERPINC1 Immunohistochemistry Kit | IHC |
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