AbPlus™ Anti-SET Magnetic Beads (VS-0724-YC1084) (CAT#: VS-0724-YC1084)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-SET specific antibody

• Target
• SET

• Immunogen
• Synthetic peptide corresponding to the N-terminus of the human SET.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

• Alternative Names
• SET Nuclear Proto-Oncogene; Template-Activating Factor-I, Chromatin Remodelling Factor; SET Translocation (Myeloid Leukemia-Associated); Inhibitor Of Granzyme A-Activated DNase; Protein Phosphatase Type 2A Inhibitor; Phosphatase 2A Inhibitor I2PP2A; HLA-DR-Associated Protein II; PHAPII; IGAAD; TAF-I;

• Gene ID
• 6418

• UniProt ID
• Q01105

Select a product category from the dropdown menu below to view related products.