AbPlus™ Anti-SIRT1 Magnetic Beads (VS-0724-YC526) (CAT#: VS-0724-YC526)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magnetic bead

• Bead Ligand
• Anti-SIRT1 specific antibody

• Target
• SIRT1

• Immunogen
• Recombinant human SIRT1, aa 193-747.

• Target Species
• Human

• Bead Capacity
• 40 mg/mL

• Bead size
• 25 μm

• Format
• Suspension

• Concentration
• 2 mg/mL

• Buffer
• PBS, pH 7.4

• Preservative
• 0.1% Sodium azide

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]

• Alternative Names
• Sirtuin 1; Regulatory Protein SIR2 Homolog 1; SIR2-Like Protein 1; SIR2L1; Sirtuin (Silent Mating Type Information Regulation 2, S. Cerevisiae, Homolog) 1; Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. Cerevisiae); NAD-Dependent Protein Deacetylase Sirtuin-1;

• Gene ID
• 23411

• UniProt ID
• Q96EB6

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