AbPlus™ Anti-SLAMF6 Magnetic Beads (VS-0724-YC729)
CAT#: VS-0724-YC729
The AbPlus Anti-SLAMF6 Magnetic Beads (VS-0724-YC729) is an innovative affinity resin which is bound with anti-SLAMF6 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SLAMF6 protein under native and denaturing conditions.
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51363/1770_E2_2_selected.jpg
Subcellular Location and Protein Expression
Figure 2 IHC staining of human tonsil
Immunohistochemical staining of human tonsil shows moderate positivity in germinal center and non-germinal center cells.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51363/119554_A_6_8_selected.jpg
Subcellular Location and Protein Expression
Figure 3 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & cytosol.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51363/1886_H5_1_blue_red_green.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51903/119543_A_8_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51363/119554_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51903/119543_A_4_6.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51363/119554_A_7_8.jpg
Normal Tissue
Figure 8 Tonsil
Germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/51363/119554_A_6_8.jpg
RNA Expression
Figure 9 RNA cell line category: Group enriched (Daudi, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000162739-SLAMF6
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-SLAMF6 specific antibody
- Target
- SLAMF6
- Immunogen
- Recombinant human SLAMF6 fragment derived from E. coli.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010]
- Alternative Names
- SLAM Family Member 6; Activating NK Receptor; NK-T-B-Antigen; NTB-A; KALI; Natural Killer-, T- And B-Cell Antigen; NTBA Receptor;
- Gene ID
- 114836
- UniProt ID
- Q96DU3
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CITATIONS
RESOURCES
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Downloadable Resources
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Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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| TAB-602MZ-S(P) | Mouse Anti-SLAMF6 Recombinant Antibody; scFv Fragment (TAB-602MZ-S(P)) | Internalization assay, FC | Mouse scFv |
| TAB-603MZ-S(P) | Mouse Anti-SLAMF6 Recombinant Antibody; scFv Fragment (TAB-603MZ-S(P)) | FC, WB | Mouse scFv |
| TAB-604MZ-S(P) | Mouse Anti-SLAMF6 Recombinant Antibody; scFv Fragment (TAB-604MZ-S(P)) | FC, WB | Mouse scFv |
| TAB-601MZ-F(E) | Mouse Anti-SLAMF6 Recombinant Antibody; Fab Fragment (TAB-601MZ-F(E)) | Internalization assay, FC | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0073CT | Recombinant Mouse anti-Human SLAMF6 Monoclonal antibody (OU-8) | FC, IP | |
| FN-191CQ | Recombinant Mouse Anti-SLAMF6 Antibody (13G3-19D) | FC, FuncS, IP, WB, Block | Mouse IgG2a, κ |
| MOB-067YJL | Mouse Anti-SLAMF6 Recombinant Antibody (clone CBS211) | FC, ELISA, Neut | Mouse IgG2a |
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| VS13-YC1061 | Rabbit Anti-SLAMF6 Recombinant Antibody (VS13-YC1061) | WB, ICC, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1973CQ | Recombinant Mouse Anti-SLAMF6 Antibody (NT-7) | FC, BL | IgG1, κ |
| CAT | Product Name | Application | Type |
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| MOR-3278 | Hi-Affi™ Recombinant Rabbit Anti-Slamf6 Monoclonal Antibody (DS3278AB) | WB, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY198 | CytoStream™ Mouse Anti-SLAMF6 Recombinant Antibody (VS-0225-XY198) | FC | Mouse IgG2a, kappa |
| VS13-YC1060 | CytoStream™ Rabbit Anti-SLAMF6 Recombinant Antibody (VS13-YC1060) | FC, ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC40 | Recombinant Anti-Slamf6 Vesicular Antibody, EV Displayed (VS-0425-YC40) | ELISA, FC, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6619 | Anti-SLAMF6 Immunohistochemistry Kit | IHC |
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