Product Property

Clonality
Monoclonal Antibody

Purification
Protein G purified

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS, pH 7.4

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
Solute Carrier Family 10 Member 1; Solute Carrier Family 10 (Sodium/Bile Acid Cotransporter), Member 1; Sodium/Taurocholate Cotransporting Polypeptide; Cell Growth-Inhibiting Gene 29 Protein; Na(+)/Taurocholate Transport Protein; Na(+)/Bile Acid Cotransporter; NTCP

Gene ID
6554

UniProt ID
Q14973

Long Name
Solute Carrier Family 10 Member 1

Sequence Similarities
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.

Cellular Localization
Cell membrane

Post Translation Modifications
Glycosylation at Asn5, Asn11, Asn117, and Asn336 (NX_Q14973 [NX_Q14973-1])
Modification sites at PhosphoSitePlus (Q14973)
Glycosylation from GlyGen (Q14973) 4 sites

Protein Refseq
NP_003040.1

Function
It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate (PubMed:14660639, 34060352).
Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation (PubMed:33222321).

Recommended Products

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

See other products for "SLC10A1"