Mouse Anti-SLC10A1 Recombinant Antibody (clone YN69083)
CAT#: VS-0624-FY33
This mouse recombinant monoclonal antibody illustrates a strong affinity for the human SLC10A1 protein, originating from a hybridoma cell line.
Gene Expression
Normal Tissue
Figure 1 IHC staining of human liver
Immunohistochemical staining of human liver shows membrane positivity in hepatocytes.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42727/ihc_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42727/95206_B_7_5.jpg
Normal Tissue
Figure 3 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42727/95206_A_8_3.jpg
Normal Tissue
Figure 4 Liver
Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42727/95206_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/42727/95206_A_9_5.jpg
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human SLC10A1
- Species Reactivity
- Human
- Clone
- YN69083
- Applications
- Immunoassay
- Related Disease
- Hypercholanemia, Familial, 2 and Familial Hypercholanemia
Product Property
- Clonality
- Monoclonal Antibody
- Purification
- Protein G purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS, pH 7.4
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Solute Carrier Family 10 Member 1; Solute Carrier Family 10 (Sodium/Bile Acid Cotransporter), Member 1; Sodium/Taurocholate Cotransporting Polypeptide; Cell Growth-Inhibiting Gene 29 Protein; Na(+)/Taurocholate Transport Protein; Na(+)/Bile Acid Cotransporter; NTCP
- Gene ID
- 6554
- UniProt ID
- Q14973
- Long Name
- Solute Carrier Family 10 Member 1
- Sequence Similarities
- Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
- Cellular Localization
- Cell membrane
- Post Translation Modifications
- Glycosylation at Asn5, Asn11, Asn117, and Asn336 (NX_Q14973 [NX_Q14973-1])
Modification sites at PhosphoSitePlus (Q14973)
Glycosylation from GlyGen (Q14973) 4 sites
- Protein Refseq
- NP_003040.1
- Function
- It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate (PubMed:14660639, 34060352).
Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation (PubMed:33222321).
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Customer Review
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Effective in Assays
The mouse recombinant antibody against SLC10A1 displays impressive affinity with a purity exceeding 95% as determined by SDS-PAGE. I have used it in immunoassays with encouraging outcomes, specifically noting its strong binding property and reliable performance.
Great Binding
This anti-SLC10A1 antibody has provided consistent and reliable results in our assays. The protein G purified reagent exhibits a high level of specificity to the human SLC10A1 target and works well in immunoassay formats. I appreciate its robust performance and reproducible data.
User 193*****26Suitable for WB
I used this antibody in our lab for western blot. It gave nice clear bands at 1:500.
Q&As
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Can I use this antibody for immunoassay applications?
A: Yes, the mouse anti-SLC10A1 recombinant antibody has been successfully used in immunoassays. Its specificity for the SLC10A1 protein and the high purity (>95% by SDS-PAGE), achieved through Protein G purification, ensure reliable results in various assay formats.
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How is the performance of this antibody validated?
A: The performance of this antibody has been validated through multiple immunoassay formats, with emphasis on its strong binding to human SLC10A1. The>95% purity, confirmed by SDS-PAGE, and the consistent performance in test assays make it a reliable choice in research.
View the frequently asked questions answered by Creative Biolabs Support.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# VS-0624-FY33, RRID: AB_3714386)
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
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COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Secondary Antibody
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- Product Name
See other products for "SLC10A1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3936z | Mouse Anti-SLC10A1 Recombinant Antibody (clone 43H2) | WB, IHC, FC | Mouse IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3280 | Hi-Affi™ Recombinant Rabbit Anti-SLC10A1 Monoclonal Antibody (DS3280AB) | WB, ICC | IgG |
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