Rabbit Anti-SLC25A12 Recombinant Antibody (clone R06-9E3) (CAT#: VS3-FY1881)

• Immunogen
• Synthetic peptide of human SLC25A12

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human, Mouse and Rat SLC25A12

• Species Reactivity
• Human, Mouse, Rat

• Clone
• R06-9E3

• Applications
• Western Blot, Immunoprecipitation

• MW
• The calculated weight of the target protein is approximately 75 kDa, while the observed molecular weight stands at 75 kDa.

• Related Disease
• Developmental And Epileptic Encephalopathy 39 With Leukodystrophy and Developmental And Epileptic Encephalopathy 1

• Purification
• Affinity Purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Western Blot: 1/500-1/1000
  Immunoprecipitation: 1/20

• Alternative Names
• Solute Carrier Family 25 Member 12; Solute Carrier Family 25 (Mitochondrial Carrier, Aralar), Member 12; Solute Carrier Family 25 (Aspartate/Glutamate Carrier), Member 12; Mitochondrial Aspartate Glutamate Carrier 1; Calcium Binding Mitochondrial Carrier Superfamily Member Aralar1; Calcium-Binding Mitochondrial Carrier Protein Aralar1

• Gene ID
• 8604

• UniProt ID
• O75746

• Sequence Similarities
• Belongs to the mitochondrial carrier (TC 2.A.29) family.

• Cellular Localization
• Membrane, Mitochondrion, Mitochondrion inner membrane

• Protein Refseq
• NP_003696.2

• Function
• Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle.
  Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation.

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

Secondary Antibody

• 2ND-054CQ
• Goat Anti-Rabbit IgG Antibody, R-PE

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-055CQ
• Chicken Anti-Rabbit IgG (H&L) Antibody

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