Rabbit Anti-SLC25A12 Recombinant Antibody (VS13-YC1065)

CAT#: VS13-YC1065

The Rabbit Anti-SLC25A12 Recombinant Antibody is specific for human, mouse and rat SLC25A12. SLC25A12 encodes a mitochondrial carrier protein exchanging aspartate for glutamate, linked to autism and hypomyelination. The anti-SLC25A12 antibody can be used for Western blot (1/500-1/1000), Immunoprecipitation (1/20).

Specifications

  • Immunogen
  • Recombinant human SLC25A12.
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat SLC25A12
  • Species Reactivity
  • Human, Mouse, Rat
  • Applications
  • WB, IP
  • Conjugate
  • NONE

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Affinity Chromatography purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
  • Preservative
  • 0.01% Sodium azide
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Shipping with ice pack.

Applications

  • Application Notes
  • Western blot (WB): 1/500-1/1000
    Immunoprecipitation (IP): 1/20

Target

  • Alternative Names
  • Solute Carrier Family 25 Member 12; Solute Carrier Family 25 (Mitochondrial Carrier, Aralar), Member 12; Solute Carrier Family 25 (Aspartate/Glutamate Carrier), Member 12; Mitochondrial Aspartate Glutamate Carrier 1; Calcium Binding Mitochondrial Carrier Superfamily Member Aralar1; Calcium-Binding Mitochondrial Carrier Protein Aralar1;
  • Long Name
  • Solute Carrier Family 25 Member 12
  • Sequence Similarities
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Cellular Localization
  • Membrane; Mitochondrion; Mitochondrion inner membrane
  • Function
  • Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (PubMed:11566871, PubMed:19641205, PubMed:24515575).
    Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation (PubMed:11566871).
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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Secondary Antibody

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