Rabbit Anti-SLC25A12 Recombinant Antibody (VS13-YC1065) (CAT#: VS13-YC1065)

The Rabbit Anti-SLC25A12 Recombinant Antibody is specific for human, mouse and rat SLC25A12. SLC25A12 encodes a mitochondrial carrier protein exchanging aspartate for glutamate, linked to autism and hypomyelination. The anti-SLC25A12 antibody can be used for Western blot (1/500-1/1000), Immunoprecipitation (1/20).

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Specifications

  • Immunogen
  • Recombinant human SLC25A12.
  • Host Species
  • Rabbit
  • Type
  • Rabbit IgG
  • Specificity
  • Human, Mouse and Rat SLC25A12
  • Species Reactivity
  • Human, Mouse, Rat
  • Applications
  • WB, IP
  • Conjugate
  • NONE

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Affinity Chromatography purified
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.
  • Preservative
  • 0.01% Sodium azide
  • Storage
  • Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
  • Shipping
  • Shipping with ice pack.

Applications

  • Application Notes
  • Western blot (WB): 1/500-1/1000
    Immunoprecipitation (IP): 1/20

Target

  • Alternative Names
  • Solute Carrier Family 25 Member 12; Solute Carrier Family 25 (Mitochondrial Carrier, Aralar), Member 12; Solute Carrier Family 25 (Aspartate/Glutamate Carrier), Member 12; Mitochondrial Aspartate Glutamate Carrier 1; Calcium Binding Mitochondrial Carrier Superfamily Member Aralar1; Calcium-Binding Mitochondrial Carrier Protein Aralar1;
  • Long Name
  • Solute Carrier Family 25 Member 12
  • Sequence Similarities
  • Belongs to the mitochondrial carrier (TC 2.A.29) family.
  • Cellular Localization
  • Membrane; Mitochondrion; Mitochondrion inner membrane
  • Function
  • Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (PubMed:11566871, PubMed:19641205, PubMed:24515575).
    Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation (PubMed:11566871).

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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