Rabbit Anti-SLC27A4 Recombinant Antibody (VS13-YC1066) (CAT#: VS13-YC1066)

• Immunogen
• Recombinant human FATP4.

• Host Species
• Rabbit

• Type
• Rabbit IgG

• Specificity
• Human SLC27A4

• Species Reactivity
• Human

• Applications
• WB, ICC, IF, IP

• Conjugate
• NONE

• Clonality
• Monoclonal

• Purification
• Affinity Chromatography purified

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Buffer
• 50 mM Tris-Glycine (pH 7.4) containing 150 mM NaCl, 40% Glycerol and 0.05% BSA.

• Preservative
• 0.01% Sodium azide

• Storage
• Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

• Shipping
• Shipping with ice pack.

• Application Notes
• Western blot (WB): 1/500-1/1000
  Immunofluorescence (IF): 1/50-1/200
  Immunoprecipitation (IP): 1/20

• Alternative Names
• Solute Carrier Family 27 Member 4; Solute Carrier Family 27 (Fatty Acid Transporter), Member 4; ACSVL4; FATP4; Long-Chain Fatty Acid Transport Protein 4; Fatty Acid Transport Protein 4;

• Gene ID
• 10999

• UniProt ID
• Q6P1M0

• Long Name
• Solute Carrier Family 27 Member 4

• Sequence Similarities
• Belongs to the ATP-dependent AMP-binding enzyme family.

• Cellular Localization
• Endoplasmic reticulum; Membrane

• Protein Refseq
• NP_005085.2

• Function
• Mediates the levels of long-chain fatty acids (LCFA) in the cell by facilitating their transport across cell membranes (PubMed:10518211, PubMed:12556534, PubMed:20448275, PubMed:21395585, PubMed:22022213).
  Appears to be the principal fatty acid transporter in small intestinal enterocytes (PubMed:20448275).
  Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (PubMed:22022213, PubMed:24269233).
  Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis (By similarity).
  Probably involved in fatty acid transport across the blood barrier (PubMed:21395585).
  Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).

Secondary Antibody

• 2ND-059CQ
• Goat Anti-Rabbit IgG (H&L) Antibody

• 2ND-061CQ
• Sheep Anti-Rabbit IgG (H&L) Antibody

Isotype Control

• MOB-208CQ
• Rabbit IgG Isotype Control Antibody

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