AbPlus™ Anti-SMPD1 Magnetic Beads (CBL631) (CAT#: VS-0424-XY240)

• Applications
• Immunoprecipitation, Protein Purification

• Matrix
• Magrose bead (> 50 μmol/mL gel)

• Bead Ligand
• Anti-SMPD1 specific antibody (CBL631)

• Target
• SMPD1

• Immunogen
• Recombinant human SMPD1 isoform 1

• Target Species
• Human

• Antibody Clone
• CBL631

• Bead Capacity
• 20-30 mg/mL binding antibody

• Bead size
• 10-37 μm

• Stability
• pH 2-14

• Format
• 20% Suspension

• Buffer
• PBS, pH 7.4, with 1% BSA

• Preservative
• 0.03% Proclin 300

• Storage
• Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

• Application Notes
• The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

• Introduction
• The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.

• Alternative Names
• SMPD1; sphingomyelin phosphodiesterase 1; sphingomyelin phosphodiesterase 1

• Gene ID
• 6609

• UniProt ID
• P17405

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