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Chicken Anti-SNRPA Recombinant Antibody (clone U13D12); Fab Fragment (CAT#: FAMAB-0008JF-F(E))

This product is a Fab fragment of a chicken monoclonal antibody that specifically binds to human SNRPA (U1A). Its full-length antibody was generated by a selection of phage clones with high affinities. This product may be used in the immunotherapy of mixed connective tissue disease and systemic lupus erythematosus.


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  • Datasheet
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  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/54834/if_selected.jpg
Figure 2 IF staining of human cell line A-431
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4652/if_selected.jpg
Normal Tissue
Figure 3 Lymph node
Figure 3 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46440/135412_A_9_8.jpg
Figure 4 Cerebral cortex
Figure 4 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glial cells Staining: High Intensity: Strong Quantity:>75% Location: nuclear Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46440/135412_B_7_5.jpg
Figure 5 Colon
Figure 5 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46440/135412_A_9_3.jpg
Figure 6 Liver
Figure 6 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46440/135412_A_7_4.jpg
Figure 7 Kidney
Figure 7 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/46440/135412_A_8_5.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000077312-SNRPA

Specifications

  • Immunogen
  • Antigen mixture 1 (annexin XI, centromere protein B, DNA topoisomerase I, histidyl tRNA synthetase, Ro60, Rpp38 and U1A) and mixture 2 (a-fodrin, human Pop1 protein, heat shock protein B3, Ro52, Rpp30, Rrp4 and Rrp42)
  • Host Species
  • Chicken
  • Derivation
  • Chicken phage display scFv library
  • Type
  • Chicken Fab
  • Specificity
  • Human SNRPA
  • Species Reactivity
  • Human
  • Clone
  • U13D12
  • Applications
  • IB, WB, ELISA, FuncS
  • Related Disease
  • Mixed Connective Tissue Disease, Systemic lupus erythematosus

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • U1A; Mud1; U1-A

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone U13D12"

See other products for "SNRPA"

Recombinant Antibody

CAT Product Name Application Type
MOB-1712z Mouse Anti-SNRPA Recombinant Antibody (clone 31D12) WB, ELISA, IF, IHC, IP Mouse IgG2b, κ
MOB-2133CT Recombinant Mouse anti-Human SNRPA Monoclonal antibody (EML717) ICC/IF, IHC-P, WB
MRO-1547-CN Recombinant Rabbit Anti-SNRPA Monoclonal Antibody (JB33-48) WB, IF, IHC, IP Rabbit IgG
FAMAB-0008JF Chicken Anti-SNRPA Recombinant Antibody (clone U13D12) WB, IF, Inhib, FuncS, IHC

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3357 Hi-Affi™ Recombinant Rabbit Anti-SNRPA Monoclonal Antibody (DS3357AB) WB, IP, ICC/IF IgG

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC1938 PE-A*02:01/Human SNRPA (NQFPGFKEV) MHC Tetramer FCM

scFv Fragment Antibody

CAT Product Name Application Type
FAMAB-0008JF-S(P) Chicken Anti-SNRPA Recombinant Antibody (clone U13D12); scFv Fragment IB, WB, ELISA, FuncS Chicken scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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