Chicken Anti-SNRPA Recombinant Antibody (clone U13D12) (CAT#: FAMAB-0008JF)
This product is a recombinant chicken monoclonal antibody that specifically binds to human SNRPA (U1A). The chicken antibody was generated by a selection of phage clones with high affinities. This anti-SNRPA antibody U13D12 may be used in the immunotherapy of mixed connective tissue disease and systemic lupus erythematosus.
Specific Inquiry
IHC
Figure 1 SNRPA expression is correlated with GC prognosis.
The protein expression of SNRPA was performed with immunohistochemical staining on a GC tissue microarray.
Dou, N., Yang, D., Yu, S., Wu, B., Gao, Y., & Li, Y. (2018). SNRPA enhances tumour cell growth in gastric cancer through modulating NGF expression. Cell proliferation, 51(5), e12484.
WB
Figure 2 The expression of SNRPA was evaluated by western blot in 5 gastric cancer cell lines.
SNRPA depletion inhibits GC cell growth.
Dou, N., Yang, D., Yu, S., Wu, B., Gao, Y., & Li, Y. (2018). SNRPA enhances tumour cell growth in gastric cancer through modulating NGF expression. Cell proliferation, 51(5), e12484.
IF
Figure 3 Cell growth was examined by CCK8 method in SNRPA overexpressed SGC7901 cell.
SNRPA enhances GC cell proliferation.
Dou, N., Yang, D., Yu, S., Wu, B., Gao, Y., & Li, Y. (2018). SNRPA enhances tumour cell growth in gastric cancer through modulating NGF expression. Cell proliferation, 51(5), e12484.
Inhib
Figure 4 SNRPA depletion inhibits GC cell growth.
The effects of SNRPA knockdown on cell proliferation in AGS and BGC823 cells.
Dou, N., Yang, D., Yu, S., Wu, B., Gao, Y., & Li, Y. (2018). SNRPA enhances tumour cell growth in gastric cancer through modulating NGF expression. Cell proliferation, 51(5), e12484.
FuncS
Figure 5 Cell colonies were photographed and counted after 2 wk.
Data are representative of at least 3 independent experiments.
Dou, N., Yang, D., Yu, S., Wu, B., Gao, Y., & Li, Y. (2018). SNRPA enhances tumour cell growth in gastric cancer through modulating NGF expression. Cell proliferation, 51(5), e12484.
Specifications
- Immunogen
- Antigen mixture 1 (annexin XI, centromere protein B, DNA topoisomerase I, histidyl tRNA synthetase, Ro60, Rpp38 and U1A) and mixture 2 (a-fodrin, human Pop1 protein, heat shock protein B3, Ro52, Rpp30, Rrp4 and Rrp42)
- Host Species
- Chicken
- Derivation
- Chicken phage display scFv library
- Specificity
- Human SNRPA
- Species Reactivity
- Human
- Clone
- U13D12
- Applications
- WB, IF, Inhib, FuncS, IHC
- Related Disease
- Mixed Connective Tissue Disease, Systemic lupus erythematosus
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The SNRPA antibody has been reported in applications of Western Blot, Immunofluorescence, Inhibition, Immunohistochemistry, Functional Assay.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1712z | Mouse Anti-SNRPA Recombinant Antibody (clone 31D12) | WB, ELISA, IF, IHC, IP | Mouse IgG2b, κ |
| MOB-2133CT | Recombinant Mouse anti-Human SNRPA Monoclonal antibody (EML717) | ICC/IF, IHC-P, WB | |
| MRO-1547-CN | Recombinant Rabbit Anti-SNRPA Monoclonal Antibody (JB33-48) | WB, IF, IHC, IP | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3357 | Hi-Affi™ Recombinant Rabbit Anti-SNRPA Monoclonal Antibody (DS3357AB) | WB, IP, ICC/IF | IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1938 | PE-A*02:01/Human SNRPA (NQFPGFKEV) MHC Tetramer | FCM |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0008JF-F(E) | Chicken Anti-SNRPA Recombinant Antibody (clone U13D12); Fab Fragment | IB, WB, ELISA, FuncS | Chicken Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0008JF-S(P) | Chicken Anti-SNRPA Recombinant Antibody (clone U13D12); scFv Fragment | IB, WB, ELISA, FuncS | Chicken scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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