Afuco™ Anti-SOST ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-115)
CAT#: AFC-TAB-115
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to SOST. It binds SOST, a negative regulator of osteoblast activity. Blocking SOST activity can lead to increased bone density.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Group enriched (HaCaT, SuSa)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167941-SOST
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Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Applications
- FuncS, IF, Neut, ELISA, FC, IP
- Conjugate
- Unconjugated
- Generic Name
- Blosozumab
- Related Disease
- Postmenopausal women osteoporosis
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Biosimilar Overview
Please refer to Blosozumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Blosozumab.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
See other products for "Blosozumab"
DrugMonitor™ Anti-Blosozumab Antibody (VS-1224-YC210)Blosozumab has been involved in trials studying the science and treatment of Osteoporosis and Postmenopausal Osteoporosis. The DrugMonitor™ Anti-Blosozumab Antibody (VS-1224-YC210) is an anti-drug antibody (ADA) against Blosozumab. This drug-based antibody is raised in mice immunized with the Blosozumab. The anti-Blosozumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Blosozumab in samples.
See other products for "SOST"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2432z | Mouse Anti-SOST Recombinant Antibody (clone 44A4) | WB, ELISA | Mouse IgG2b |
| HPAB-1421-FY | Rat Anti-SOST Recombinant Antibody (HPAB-1421-FY) | ELISA | Chimeric (mouse/rat) IgG |
| HPAB-1422-FY | Human Anti-SOST Recombinant Antibody (HPAB-1422-FY) | ELISA | Humanized IgG |
| HPAB-1423-FY | Human Anti-SOST Recombinant Antibody (HPAB-1423-FY) | ELISA | Humanized IgG |
| HPAB-1424-FY | Human Anti-SOST Recombinant Antibody (HPAB-1424-FY) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-116 | Human Anti-SOST Recombinant Antibody (TAB-116) | IF, IP, Neut, FuncS, ELISA, FC, ICC | Human IgG2, κ |
| TAB-580CL | Human Anti-SOST Recombinant Antibody (TAB-580CL) | ELISA, WB | Human IgG |
| TAB-411CT | Humanized Anti-SOST Recombinant Antibody (TAB-411CT) | ELISA, Neut | Humanized antibody |
| TAB-412CT | Humanized Anti-SOST Recombinant Antibody (TAB-412CT) | ELISA, Neut | Humanized antibody |
| TAB-413CT | Humanized Anti-SOST Recombinant Antibody (TAB-413CT) | ELISA, Neut | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-558CL | Afuco™ Anti-SOST Recombinant Antibody (AFC-558CL), ADCC Enhanced | ELISA, WB | Humanized IgG1 |
| AFC-TAB-116 | Afuco™ Anti-SOST Recombinant Antibody (AFC-TAB-116), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-384CT | Llama Anti-SOST Recombinant Antibody (TAB-384CT) | WB, ELSA, FC | Llama VHH |
| TAB-385CT | Anti-Human SOST Single Domain Antibody (TAB-385CT), Research Grade Biosimilar | WB, ELSA, FC | Single domain antibody |
| TAB-386CT | Anti-Human SOST Single Domain Antibody (TAB-386CT), Research Grade Biosimilar | WB, ELSA, FC | Single domain antibody |
| HPAB-1612-FY | Llama Anti-SOST Recombinant Antibody (HPAB-1612-FY) | ELISA | Llama VHH |
| HPAB-1613-FY | Llama Anti-SOST Recombinant Antibody (HPAB-1613-FY) | ELISA | Llama VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-393CT | Anti-Human SOST Recombinant Antibody (DM4) | ELISA, Neut | Human antibody |
| TAB-394CT | Human Anti-SOST Recombinant Antibody (TAB-394CT) | ELISA, Neut | Human IgG2, κ |
| TAB-395CT | Human Anti-SOST Recombinant Antibody (TAB-395CT) | ELISA, Neut | Human IgG2, κ |
| TAB-396CT | Human Anti-SOST Recombinant Antibody (TAB-396CT) | ELISA, Neut | Human IgG2, κ |
| TAB-397CT | Human Anti-SOST Recombinant Antibody (TAB-397CT) | ELISA | Human IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4434 | Hi-Affi™ Recombinant Rabbit Anti-SOST Monoclonal Antibody (SI527DS) | ELISA | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0342-YC-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0342-YC-S(P)) | Neut, FuncS | Humanized scFv |
| HPAB-0343-YC-S(P) | Mouse Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0343-YC-S(P)) | FuncS | Mouse scFv |
| HPAB-0344-YC-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0344-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-1122LY-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-1122LY-S(P)) | ELISA | Human scFv |
| HPAB-1123LY-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-1123LY-S(P)) | ELISA, Block | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0579-WJ-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0579-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0580-WJ-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0580-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0581-WJ-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0581-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0582-WJ-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0582-WJ-F(E)) | ELISA | Human Fab |
| HPAB-0583-WJ-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0583-WJ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY246 | AbPlus™ Anti-SOST Magnetic Beads (VS-0424-XY2446) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY180 | Human Anti-SOST scFv-Fc Chimera (VS-0425-FY180) | Inhib, ELISA | Human IgG2, scFv-Fc |
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