Afuco™ Anti-SOST ADCC Recombinant Antibody (Blosozumab), ADCC Enhanced (CAT#: AFC-TAB-115)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to SOST. Blosozumab binds SOST, a negative regulator of osteoblast activity. Blocking SOST activity can lead to increased bone density.
Specific Inquiry
RNA Expression
Figure 1 RNA cell line category: Group enriched (HaCaT, SuSa)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167941-SOST
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000167941-SOST
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Blosozumab
- Applications
- FuncS, IF, Neut, ELISA, FC, IP
- Conjugate
- Unconjugated
- Generic Name
- Blosozumab
- Related Disease
- Postmenopausal women osteoporosis
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Blosozumab; 1132758-87-2; LY2541546; SOST; sclerostin; sclerosteosis; VBCH;
- Gene ID
- 50964
- UniProt ID
- Q9BQB4
Related Resources
Please refer to Blosozumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Blosozumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Blosozumab"
Anti-Human SOST Recombinant Antibody (Blosozumab)Recombinant monoclonal antibody to SOST. Blosozumab binds SOST, a negative regulator of osteoblast activity. Blocking SOST activity can lead to increased bone density.
See other products for "SOST"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-116 | Human Anti-SOST Recombinant Antibody (TAB-116) | IF, IP, Neut, FuncS, ELISA, FC, ICC | Human IgG2, κ |
| TAB-580CL | Human Anti-SOST Recombinant Antibody (TAB-580CL) | ELISA, WB | Human IgG |
| TAB-411CT-S(P) | Humanized Anti-SOST Recombinant Antibody; scFv Fragment (TAB-411CT-S(P)) | ELISA, Neut | Humanized scFv |
| TAB-411CT-F(E) | Humanized Anti-SOST Recombinant Antibody; Fab Fragment (TAB-411CT-F(E)) | ELISA, Neut | Humanized Fab |
| TAB-412CT-F(E) | Humanized Anti-SOST Recombinant Antibody; Fab Fragment (TAB-412CT-F(E)) | ELISA, Neut | Humanized Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-558CL | Afuco™ Anti-SOST Recombinant Antibody (AFC-558CL), ADCC Enhanced | ELISA, WB | Humanized IgG1 |
| AFC-TAB-116 | Afuco™ Anti-SOST Recombinant Antibody (AFC-TAB-116), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | Human IgG1, κ |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-384CT | Llama Anti-SOST Recombinant Antibody (TAB-384CT) | WB, ELSA, FC | Llama VHH |
| TAB-385CT | Anti-Human SOST Therapeutic Single Domain Antibody (3-F1) | WB, ELSA, FC | Single domain antibody |
| TAB-386CT | Anti-Human SOST Therapeutic Single Domain Antibody (7-G5) | WB, ELSA, FC | Single domain antibody |
| TAB-387CT | Anti-Human SOST Therapeutic Single Domain Antibody (2-F6) | WB, ELSA, FC | Single domain antibody |
| TAB-388CT | Anti-Human SOST Therapeutic Single Domain Antibody (6-E12) | WB, ELSA, FC | Single domain antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-393CT | Anti-Human SOST Recombinant Antibody (DM4) | ELISA, Neut | Human antibody |
| TAB-394CT | Human Anti-SOST Recombinant Antibody (TAB-394CT) | ELISA, Neut | Human IgG2, κ |
| TAB-395CT | Human Anti-SOST Recombinant Antibody (TAB-395CT) | ELISA, Neut | Human IgG2, κ |
| TAB-396CT | Human Anti-SOST Recombinant Antibody (TAB-396CT) | ELISA, Neut | Human IgG2, κ |
| TAB-410CT | Human Anti-SOST Recombinant Antibody (TAB-410CT) | ELISA | Human IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4434 | Hi-Affi™ Recombinant Rabbit Anti-SOST Monoclonal Antibody (SI527DS) | ELISA | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0342-YC-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0342-YC-F(E)) | Neut, FuncS | Humanized Fab |
| HPAB-0343-YC-F(E) | Mouse Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0343-YC-F(E)) | FuncS | Mouse Fab |
| HPAB-0344-YC-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0344-YC-F(E)) | ELISA, FuncS | Human Fab |
| HPAB-0464-CN-F(E) | Mouse Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-0464-CN-F(E)) | ELISA, Block | Mouse Fab |
| PFBC-402 | Human Anti-SOST Recombinant Antibody; Fab Fragment (PFBC-402) | IHC, Neut | Human Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0579-WJ | Human Anti-SOST Recombinant Antibody (HPAB-0579-WJ) | ELISA | Human IgG |
| HPAB-0580-WJ | Human Anti-SOST Recombinant Antibody (HPAB-0580-WJ) | ELISA | Human IgG |
| HPAB-0581-WJ | Human Anti-SOST Recombinant Antibody (HPAB-0581-WJ) | ELISA | Human IgG |
| HPAB-0582-WJ | Human Anti-SOST Recombinant Antibody (HPAB-0582-WJ) | ELISA | Human IgG |
| HPAB-0583-WJ | Human Anti-SOST Recombinant Antibody (HPAB-0583-WJ) | ELISA | Human IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1421-FY-F(E) | Mouse Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-1421-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-1422-FY-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-1422-FY-F(E)) | ELISA | Humanized Fab |
| HPAB-1423-FY-F(E) | Human Anti-SOST Recombinant Antibody; Fab Fragment (HPAB-1423-FY-F(E)) | ELISA | Humanized Fab |
| HPAB-0920-WJ-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0920-WJ-S(P)) | ELISA | Humanized scFv |
| HPAB-0921-WJ-S(P) | Human Anti-SOST Recombinant Antibody; scFv Fragment (HPAB-0921-WJ-S(P)) | ELISA | Humanized scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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