AbPlus™ Anti-SPN Magnetic Beads (VS-0724-YC806) (CAT#: VS-0724-YC806)
The AbPlus Anti-SPN Magnetic Beads (VS-0724-YC806) is an innovative affinity resin which is bound with anti-SPN specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of SPN protein under native and denaturing conditions.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line REH
(Immunofluorescent staining of human cell line REH shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55244/1817_E10_2_selected.jpg
(Immunofluorescent staining of human cell line REH shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55244/1817_E10_2_selected.jpg

Figure 2 Lung
(Macrophages
Staining:
High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55244/134325_A_2_4.jpg
(Macrophages
Staining:
High
Intensity: Strong
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55244/134325_A_2_4.jpg

Figure 3 Lymph node
(Non-germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55244/134325_A_8_8.jpg
(Non-germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55244/134325_A_8_8.jpg

Figure 4 RNA cell line category: Cell line enhanced (HEL, HL-60, HMC-1, MOLT-4, REH, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197471-SPN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197471-SPN

Figure 4 RNA cell line category: Cell line enhanced (HEL, HL-60, HMC-1, MOLT-4, REH, THP-1, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197471-SPN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197471-SPN
Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magnetic bead
- Bead Ligand
- Anti-SPN specific antibody
- Target
- SPN
- Immunogen
- Synthetic peptide corresponding to the N-terminus of the human SPN/CD43.
- Target Species
- Human
- Bead Capacity
- 40 mg/mL
- Bead size
- 25 μm
- Format
- Suspension
- Concentration
- 2 mg/mL
- Buffer
- PBS, pH 7.4
- Preservative
- 0.1% Sodium azide
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]
- Alternative Names
- Sialophorin; Sialophorin (GpL115, Leukosialin, CD43); Leukocyte Sialoglycoprotein; Galactoglycoprotein; Leukosialin; GALGP;
- Gene ID
- 6693
- UniProt ID
- P16150
Downloads
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Extracellular Vesicle (EV) Antibody Products
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1337z | Mouse Anti-SPN Recombinant Antibody (clone 22C10) | FC, ICC, IF, IHC, WB | Mouse IgG1, κ |
HPAB-3177LY | Human Anti-SPN Recombinant Antibody (HPAB-3177LY) | Inhib, IHC, FC, WB | Humanized IgG |
HPAB-3178LY | Human Anti-SPN Recombinant Antibody (HPAB-3178LY) | Inhib, IHC, FC, WB | Humanized IgG |
HPAB-3179LY | Human Anti-SPN Recombinant Antibody (HPAB-3179LY) | Inhib, IHC, FC, WB | Humanized IgG |
HPAB-3180LY | Human Anti-SPN Recombinant Antibody (HPAB-3180LY) | Inhib, IHC, FC, WB | Humanized IgG |
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