Mouse Anti-SPN Recombinant Antibody (clone 84-3C1)
CAT#: VS11-QX131
This product is a recombinant mouse antibody that specifically binds to SPN. This antibody can be used for the following applications: WB, FC, IP, IF, IHC.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line REH
Immunofluorescent staining of human cell line REH shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55244/1817_E10_2_selected.jpg
Normal Tissue
Figure 2 Lung
Macrophages
Staining:
High
Intensity: Strong
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55244/134325_A_2_4.jpg
Normal Tissue
Figure 3 Lymph node
Non-germinal center cells
Staining:
High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55244/134325_A_8_8.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (HEL, HL-60, HMC-1, MOLT-4, REH, THP-1, U-937)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197471-SPN
❮
❯
Specifications
- Immunogen
- Stimulated human leukocytes
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG2b, κ
- Specificity
- Human SPN
- Species Reactivity
- Human
- Clone
- 84-3C1
- Applications
- WB, FC, IP, IF, IHC
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- 1 mg/mL (Please refer to the vial label for the specific concentration.)
- Buffer
- 0.2 μm filtered solution in PBS
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipped at 4°C.
Target
- Alternative Names
- LSN; CD43; GALGP; GPL115; LEU-22
- Gene ID
- 6693
- UniProt ID
- P16150
- Long Name
- Leukosialin
- Cellular Localization
- Plasma membrane
- Function
- Predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration. Positively regulates T-cell trafficking to lymph-nodes via its association with ERM proteins (EZR, RDX and MSN) (By similarity). Negatively regulates Th2 cell differentiation and predisposes the differentiation of T-cells towards a Th1 lineage commitment.
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Isotype Control
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
See other products for "SPN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0285MZ | Recombinant Mouse Anti-Human Sialophorin Antibody (clone EF-T2) | IHC | Mouse antibody |
| FN-048CQ | Recombinant Mouse Anti-SPN Antibody (DFT1) | FC, FuncS, WB | Mouse IgG1 |
| ZG-0113J | Mouse Anti-SPN Recombinant Antibody (ZG-0113J) | IHC-P, IF | Mouse IgG |
| ZG-0114J | Mouse Anti-SPN Recombinant Antibody (ZG-0114J) | IHC-P, IF | Mouse IgG |
| VS3-FY1 | Recombinant Mouse Anti-SPN Antibody (clone 3E12F3) | ELISA, WB, FC, IHC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1980CQ | Recombinant Mouse Anti-Spn Antibody (L11) | BL, IP, FC, IHC | IgG2a, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3391 | Hi-Affi™ Recombinant Rabbit Anti-SPN Monoclonal Antibody (DS3391AB) | IHC-P, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-3177LY-S(P) | Human Anti-SPN Recombinant Antibody; scFv Fragment (HPAB-3177LY-S(P)) | Inhib, IHC, FC, WB | Human scFv |
| HPAB-3178LY-S(P) | Human Anti-SPN Recombinant Antibody; scFv Fragment (HPAB-3178LY-S(P)) | Inhib, IHC, FC, WB | Human scFv |
| HPAB-3179LY-S(P) | Human Anti-SPN Recombinant Antibody; scFv Fragment (HPAB-3179LY-S(P)) | Inhib, IHC, FC, WB | Human scFv |
| HPAB-3180LY-S(P) | Human Anti-SPN Recombinant Antibody; scFv Fragment (HPAB-3180LY-S(P)) | Inhib, IHC, FC, WB | Human scFv |
| HPAB-3181LY-S(P) | Human Anti-SPN Recombinant Antibody; scFv Fragment (HPAB-3181LY-S(P)) | Inhib, IHC, FC, WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-3177LY-F(E) | Human Anti-SPN Recombinant Antibody; Fab Fragment (HPAB-3177LY-F(E)) | Inhib, IHC, FC, WB | Humanized Fab |
| HPAB-3178LY-F(E) | Human Anti-SPN Recombinant Antibody; Fab Fragment (HPAB-3178LY-F(E)) | Inhib, IHC, FC, WB | Humanized Fab |
| HPAB-3179LY-F(E) | Human Anti-SPN Recombinant Antibody; Fab Fragment (HPAB-3179LY-F(E)) | Inhib, IHC, FC, WB | Humanized Fab |
| HPAB-3180LY-F(E) | Human Anti-SPN Recombinant Antibody; Fab Fragment (HPAB-3180LY-F(E)) | Inhib, IHC, FC, WB | Humanized Fab |
| HPAB-3181LY-F(E) | Human Anti-SPN Recombinant Antibody; Fab Fragment (HPAB-3181LY-F(E)) | Inhib, IHC, FC, WB | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC806 | AbPlus™ Anti-SPN Magnetic Beads (VS-0724-YC806) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY203 | CytoStream™ Mouse Anti-SPN Recombinant Antibody (VS-0225-XY203) | FC | Mouse IgG1, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY30 | Human Anti-SPN scFv-Fc Chimera (VS-0325-FY30) | ELISA, FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC504 | Recombinant Anti-SPN Vesicular Antibody, EV Displayed (VS-0425-YC504) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6864 | Anti-SPN Immunohistochemistry Kit | IHC | |
| VS-0525-XY6865 | Anti-Rat SPN Immunohistochemistry Kit | IHC |
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