Mouse Anti-SST Recombinant Antibody (clone ABT-SST)
CAT#: VS3-CJ1075
This product is a mouse antibody that recognizes human SST.
Gene Expression
Normal Tissue
Figure 1 Duodenum
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19472/164703_A_8_2_val_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Neuropil Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19472/164703_B_9_5.jpg
Normal Tissue
Figure 3 Colon
Endocrine cells Staining: High Intensity: Strong Enterocytes -
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19472/164703_A_7_3.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (EFO-21, U-2 OS, U-251 MG, U-698)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157005-SST
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Specifications
- Immunogen
- Synthesized peptide derived from human Somatostatin
- Host Species
- Mouse
- Type
- Mouse IgG2b, κ
- Specificity
- Human SST
- Species Reactivity
- Human
- Clone
- ABT-SST
- Applications
- IHC-P
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity Chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 0.5% BSA, PBS.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Immunohistochemistry-Parraffin (1:100-1:500).
Target
- Alternative Names
- SMST; SST1
- Gene ID
- 6750
- UniProt ID
- P61278
- Sequence Similarities
- Belongs to the somatostatin family.
- Cellular Localization
- Secreted
- Post Translation Modifications
- C-terminal amidation of the neuronostatin peptide is required for its biological activity, including for the regulation of mean arterial pressure.
- Protein Refseq
- NP_001039.1
- Function
- Somatostatin-14:
Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhibition of ghrelin-stimulated secretion of GH1 can be further increased by neuronostatin.
Neuronostatin:
May enhance low-glucose-induced glucagon release by pancreatic alpha cells (By similarity).
This effect may be mediated by binding to GPR107 and PKA activation (By similarity).
May regulate cardiac contractile function (By similarity).
May compromise cardiomyocyte viability (By similarity).
In the central nervous system, may impair memory retention and may affect hippocampal excitability (By similarity).
May also have anxiolytic and anorexigenic effects (By similarity).
May play a role in arterial pressure regulation (By similarity).
May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH. Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH (PubMed:29615476).
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Isotype Control
- CAT
- Product Name
Secondary Antibody
- CAT
- Product Name
Recommended Dilution Buffer
- CAT
- Product Name
See other products for "SST"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1357z | Mouse Anti-SST Recombinant Antibody (clone 25F1) | WB, ELISA, FC, IHC, ICC, IF | Mouse IgG1 |
| MOB-0248F | Mouse Anti-SST Recombinant Antibody (MOB-0248F) | IHC-P, IF | Mouse IgG |
| MOB-0249F | Mouse Anti-SST Recombinant Antibody (MOB-0249F) | IHC-P, IF | Mouse IgG |
| VS3-CJ1076 | Mouse Anti-SST Recombinant Antibody (clone PT2145) | IHC-P | Mouse IgG |
| VS3-FY1394 | Recombinant Mouse Anti-SST Antibody (clone 2G2-1B5-10A3) | IHC-P | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3413 | Hi-Affi™ Recombinant Rabbit Anti-SST Monoclonal Antibody (DS3413AB) | IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY6921 | Anti-SST Immunohistochemistry Kit | IHC | |
| VS-0525-XY6922 | Anti-Mouse SST Immunohistochemistry Kit | IHC | |
| VS-0525-XY6923 | Anti-Rat SST Immunohistochemistry Kit | IHC |
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