CytoStream™ Rabbit Anti-STMN1 Recombinant Antibody (VS13-YC1122)
CAT#: VS13-YC1122
The CytoStream™ Rabbit Anti-STMN1 Recombinant Antibody is specific for human, mouse and rat STMN1. STMN1 encodes a stathmin family protein regulating microtubules, involved in intracellular signal integration by destabilizing microtubules. The anti-STMN1 antibody was developed and selected by our CytoStream™ platform and the mAb is recommended for use in flow cytometry staining (1/50-1/100).
Gene Expression
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/10107/if_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Glial cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68438/168896_B_8_5.jpg
Normal Tissue
Figure 3 Colon
Goblet cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Mucosal lymphoid cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68438/168896_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Collecting ducts
Staining: Medium
Intensity: Strong
Quantity: <25%
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68438/168896_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Cells in seminiferous ducts
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Leydig cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68438/168896_A_6_6.jpg
Normal Tissue
Figure 6 Lymph node
Germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/68438/168896_A_7_8.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (MOLT-4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000117632-STMN1/subcellular
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Specifications
- Immunogen
- Recombinant human Stathmin 1, aa 100-149.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat STMN1
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC, IF, IHC-P, FC, IP
- Conjugate
- NONE
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- TBS (pH 7.4) containing 40% Glycerol and 0.05% BSA.
- Preservative
- 0.05% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Western blot (WB): 1/1000-1/2000
Immunocytochemistry (ICC): 1/50
Immunofluorescence (IF): 1/50-1/500
Immunohistochemistry-paraffin (IHC-P): 1/50-1/200
Flow cytometry (FC): 1/50-1/100
Target
- Alternative Names
- OP18, Oncoprotein 18
- Gene ID
- 3925
- UniProt ID
- P16949
- Long Name
- Stathmin 1
- Sequence Similarities
- Belongs to the stathmin family.
- Cellular Localization
- Cytoplasm; Cytoskeleton; Microtubule
- Protein Refseq
- NP_001138926.1; NP_005554.1; NP_981944.1
- Function
- Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity).
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Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "STMN1"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3537z | Mouse Anti-STMN1 Recombinant Antibody (clone 11H12) | WB, FC, ICC, IF, IHC | Mouse IgG2b |
| MOB-1958CT | Recombinant Mouse anti-Human STMN1 Monoclonal antibody (24) | ELISA, WB | |
| MRO-1445-CN | Recombinant Rabbit Anti-STMN1 Monoclonal Antibody (SS0453) | WB, IF, IHC, IP, FC | Rabbit IgG |
| VS3-QX1073 | Mouse Anti-STMN1 Recombinant Antibody (clone 11E1) | WB, ICC, IHC, FC | Mouse IgG2b |
| VS3-WK1933 | Recombinant Rabbit Anti-STMN1 Detection Antibody (clone R25-1X-6) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3443 | Hi-Affi™ Recombinant Rabbit Anti-STMN1 Monoclonal Antibody (DS3443AB) | IHC-P, IP, WB | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2212 | Anti-STMN1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY6991 | Anti-Human STMN1 Immunohistochemistry Kit | IHC |
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