Human Anti-STX1A Recombinant Antibody (clone 13C4) (CAT#: HPAB-0040LY)
This product is an antibody that recognizes Stx1. The antibody 13C4 can be used for immunoassay techniques such as: WB.
Specific Inquiry
Inhib
Figure 1 The 13C4 MAb inhibits the binding of Stx1 to Gb₃ in a dose-dependent manner.
The individual circles represent averages of two experiments performed in triplicate, and the error bars indicate standard deviations (± 1). The solid line represents the background (1 μg Gb₃ plus 1,000 pg of Stx1 and secondary antibody without primary antibody), while the dashed line represents Stx1 binding without the addition of the 13C4 MAb.
Smith, M. J., Carvalho, H. M., Melton-Celsa, A. R., & O'Brien, A. D. (2006). The 13C4 monoclonal antibody that neutralizes Shiga toxin type 1 (Stx1) recognizes three regions on the Stx1 B subunit and prevents Stx1 from binding to its eukaryotic receptor globotriaosylceramide. Infection and immunity, 74(12), 6992-6998.
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- Humanized IgG1
- Specificity
- Human STX1A
- Species Reactivity
- Human
- Clone
- 13C4
- Applications
- WB, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The Stx1 antibody has been reported in applications of Western Blot, Inhibition.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2912z | Mouse Anti-STX1A Recombinant Antibody (clone 38D10) | WB, IHC | Mouse IgG1 |
| VS-0223-WK76 | Rabbit Anti-STX1A Recombinant Antibody (VS-0223-WK76) | WB, IP, ICC, IHC, IHC-P | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3450 | Hi-Affi™ Recombinant Rabbit Anti-STX1A Monoclonal Antibody (DS3450AB) | IHC-P | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0040LY-S(P) | Human Anti-STX1A Recombinant Antibody (clone 13C4); scfv Fragment | WB | Humanized scfv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0040LY-F(E) | Human Anti-STX1A Recombinant Antibody (clone 13C4); Fab Fragment | WB | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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