Mouse Anti-SUZ12 Monoclonal Antibody (VS7-0425-WR936) (CAT#: VS7-0425-WR936)
This product is a mouse IgG antibody that binds to human SUZ12. The antibody can be used for WB, IHC-P, IF, and ELISA assays.
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Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoli & nuclear bodies.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/1043_A4_1_selected.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to nucleoli & nuclear bodies.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/1043_A4_1_selected.jpg
Figure 2 IHC staining of human appendix
(Immunohistochemical staining of human appendix shows nuclear positivity in lymphoid tissue and glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_1_2_selected.jpg
(Immunohistochemical staining of human appendix shows nuclear positivity in lymphoid tissue and glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_1_2_selected.jpg
Figure 3 Colon
(Glandular cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_7_3.jpg
(Glandular cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_7_3.jpg
Figure 4 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_7_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_7_5.jpg
Figure 5 Lymph node
(Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_9_8.jpg
(Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear
Non-germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/57436/132524_A_9_8.jpg
Figure 6 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000178691-SUZ12/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000178691-SUZ12/subcellular
Specifications
- Immunogen
- Recombinant human SUZ12 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human SUZ12
- Species Reactivity
- Human
- Molecule Class
- Polycomb Repressive Complex 2 Subunit
- Applications
- WB, IHC-P, IF, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Imagawa-Matsumoto syndrome (IMMAS)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- SUZ12; CHET9; JJAZ1; KIAA0160; Polycomb protein SUZ12; Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homolog
- Gene ID
- 23512
- UniProt ID
- Q15022
- Long Name
- SUZ12 polycomb repressive complex 2 subunit
- Cellular Localization
- Nucleus
- Post Translation Modifications
- Isopeptide bond; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_001308136.1
- Function
- Chromatin regulator; Repressor
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Rabbit Monoclonal Antibodies
IgG Antibodies
NHP Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3472 | Hi-Affi™ Recombinant Rabbit Anti-SUZ12 Monoclonal Antibody (DS3472AB) | WB, ICC, IF, IP | IgG |
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