Mouse Anti-SWAP70 Recombinant Antibody (VS3-FY2887) (CAT#: VS3-FY2887)

• Host Species
• Mouse

• Type
• Mouse IgG

• Specificity
• Human, Mouse, Rat, Monkey SWAP70

• Species Reactivity
• Human, Mouse, Rat, Monkey

• Applications
• Western Blot, Immunoprecipitation

• Conjugate
• Unconjugated, FITC

• Related Disease
• Aleutian Mink Disease and B-Cell Lymphoma

• Clonality
• Monoclonal Antibody

• Format
• Liquid

• Concentration
• Please refer to the vial label for the specific concentration.

• Storage
• Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

• Application Notes
• Immunoprecipitation: 1/20
  Western Blot: 1/500-1/1000

• Alternative Names
• HSPC321; SWAP-70; FLJ39540; KIAA0640

• Gene ID
• 23075

• UniProt ID
• Q9UH65

• Cellular Localization
• Cytoplasm
  Cell membrane
  Nucleus
  Cell projection, lamellipodium
  Cytoplasm, cytoskeleton

• Post Translation Modifications
• Tyrosine-phosphorylated. (Q9UH65-SWP70_HUMAN)
  Modification sites at PhosphoSitePlus (Q9UH65)
  Modification sites at neXtProt (NX_Q9UH65)
  Glycosylation from GlyGen (Q9UH65) 1 site, 1 O-linked glycan (1 site)

• Protein Refseq
• NP_055870.2

• Function
• Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC.
  It also mediates signaling of membrane ruffling.

Secondary Antibody

• 2ND-040CQ
• Goat Anti-Mouse IgG (H&L) Antibody

Isotype Control

• MRO-A1591-YJ
• Mouse IgG Isotype control, Polyclonal

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