The murine B72.3 antibody specifically recognizes the tumor-associated TAG72 antigen. The epitope of TAG72 antigen recognized by the B72.3 antibody was defined as NeuAc2-6αGαINAcα1-O-Ser/Thr (sialosyl-Tn).
Figure 1 MAb B72.3 reactivity with carcinomas.
Overnight versus30-min primary antibody incubation with formalin-fixed tissue.
Thor, A. , Ohuchi, N. , Szpak, C. A. , Johnston, W. W. , & Schlom, J. . (1986). Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody b72.3. Cancer Research, 46(6), 3118-3124.
Figure 2 Immunoperoxidase staining offormalin-fixed paraffin-embeddedmalignant tumors using MAb B72.3.
A, invasiveductal carcinoma ofthe breast,metastatic to vesselwithin hepatic triad, strongly reactive. Surrounding hepatic cells, biliary duct, and stroma are nonreactive. x 540. B, metastatic invasive ductal breast carcinoma in bone marrow demonstratescytoplasmic and membranous reactivity. x 540. C, adenocarcinomaof the colon, metastatic to the liver demonstratesgland formationandstrongMAb reactivity.x 330.D, squamouscellcarcinomaof thelung (primary)withheterogeneousstainingreactivity.x 330.E, pancreatic adenocarcinomawith focalcytoplasmicreactivity.x 220.F, gastricadenocarcinoma (signetring histologicaltype)stronglyreactive.x 330.
Thor, A. , Ohuchi, N. , Szpak, C. A. , Johnston, W. W. , & Schlom, J. . (1986). Distribution of oncofetal antigen tumor-associated glycoprotein-72 defined by monoclonal antibody b72.3. Cancer Research, 46(6), 3118-3124.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-723 | Mouse Anti-TAG72 Recombinant Antibody (clone Anatumomab); Fab Fragment | FuncS, IF, Neut, ELISA, FC, IP, WB | Mouse Fab (IgG1, κ) |
TAB-H60 | Anti-Human TAG-72 Recombinant Antibody (Satumomab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
TAB-249 | Anti-Human TAG-72 Recombinant Antibody (Minretumomab) | WB, FuncS, IF, Neut, ELISA, FC, IP | IgG1 |
TAB-002 | Anti-Human TAG72 Recombinant Antibody (Satumomab Pendetide) | IP, IF, FuncS, FC, Neut, ELISA, WB | IgG1 |
PABX-025-S (P) | Recombinant Human Anti-TAG-72 Antibody scFv Fragment (B72.3) | WB, Neut, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L070E | anti-TAG72 immunotoxin CC49 (scFv)-PE | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
PABW-119 | Human Anti-TAG72 Recombinant Antibody (clone HuCC49DeltaCH2) | WB, ELISA | Humanized IgG |
FAMAB-0278YC | Mouse Anti-TAG72 Recombinant Antibody (clone nCC49) | FuncS | Mouse IgG |
FAMAB-0279YC | Human Anti-TAG72 Recombinant Antibody (clone cCC49) | FuncS | Chimeric (mouse/human) IgG |
FAMAB-0280YC | Human Anti-TAG72 Recombinant Antibody (clone HuCC49) | FuncS | Humanized IgG |
HPAB-A1328-YJ | Human Anti-TAG-72 Recombinant Antibody (clone hum4) | ELISA, Inhib, and SPR | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBW-119 | Human Anti-TAG72 Recombinant Antibody (clone HuCC49DeltaCH2); Fab Fragment | WB, ELISA | Humanized Fab |
FAMAB-0119-CN-F(E) | Mouse Anti-TAG72 Recombinant Antibody (clone B72.3); Fab Fragment | WB, ELISA | Mouse Fab |
FAMAB-0120-CN-F(E) | Human Anti-TAG72 Recombinant Antibody (clone ccM4); Fab Fragment | WB, ELISA | Human Fab |
FAMAB-0121-CN-F(E) | Human Anti-TAG72 Recombinant Antibody (clone hmM4); Fab Fragment | WB, ELISA | Human Fab |
FAMAB-0122-CN-F(E) | Human Anti-TAG72 Recombinant Antibody (clone FV/M4); Fab Fragment | WB, ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBW-119 | Human Anti-TAG72 Recombinant Antibody (clone HuCC49DeltaCH2); scFv Fragment | WB, ELISA | Humanized scFv |
FAMAB-0315CQ-S(P) | Mouse Anti-TAG72 Recombinant Antibody (clone ACT19); scFv Fragment | ELISA | Mouse scFv |
FAMAB-0317CQ-S(P) | Mouse Anti-TAG72 Recombinant Antibody (clone CC49); scFv Fragment | WB, IP, IF, IHC, FC | Mouse scFv |
FAMAB-0119-CN-S(P) | Mouse Anti-TAG72 Recombinant Antibody (clone B72.3); scFv Fragment | WB, ELISA | Mouse scFv |
FAMAB-0120-CN-S(P) | Human Anti-TAG72 Recombinant Antibody (clone ccM4); scFv Fragment | WB, ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0285CL | Human Anti-TAG72 Recombinant Antibody (TAB-0285CL) | DB, IHC, BI, SPR | Human IgG |
TAB-0285CL-S(P) | Human Anti-TAG72 Recombinant Antibody; scFv Fragment (TAB-0285CL-S(P)) | DB, IHC, BI, SPR | Human scFv |
TAB-0286CL-S(P) | Human Anti-TAG72 Recombinant Antibody; scFv Fragment (TAB-0286CL-S(P)) | DB, IHC, BI, SPR | Human scFv |
TAB-0285CL-F(E) | Human Anti-TAG72 Recombinant Antibody; Fab Fragment (TAB-0285CL-F(E)) | DB, IHC, BI, SPR | Human Fab |
TAB-0286CL-F(E) | Human Anti-TAG72 Recombinant Antibody; Fab Fragment (TAB-0286CL-F(E)) | DB, IHC, BI, SPR | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-505CT | Humanized Anti-TAG72 Recombinant Antibody (TAB-505CT) | WB, ELISA | Humanized antibody |
TAB-505CT-S(P) | Humanized Anti-TAG72 Recombinant Antibody; scFv Fragment (TAB-505CT-S(P)) | WB, ELISA | Humanized scFv |
TAB-505CT-F(E) | Humanized Anti-TAG72 Recombinant Antibody; Fab Fragment (TAB-505CT-F(E)) | WB, ELISA | Humanized Fab |
PABX-025 | Recombinant Human Anti-TAG-72 Antibody (B72.3) | WB, Neut, FuncS, ELISA, Cyt | IgG |
PABX-025-F (E) | Recombinant Human Anti-TAG-72 Antibody Fab Fragment (B72.3 ) | WB, Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-016LC | Recombinant Anti-Human TAG-72 Antibody (Fc glycosylation) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-249 | Afuco™ Anti-TAG72 ADCC Recombinant Antibody (Minretumomab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-H60 | Afuco™ Anti-TAG72 ADCC Recombinant Antibody (Satumomab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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