Rabbit Anti-TAGLN Recombinant Antibody (VS13-YC1139) (CAT#: VS13-YC1139)
The Rabbit Anti-TAGLN Recombinant Antibody is specific for human TAGLN. TAGLN encodes an actin-binding protein acting as a tumor suppressor, involved in smooth muscle differentiation and contraction, with observed changes linked to tumor progression. The anti-TAGLN antibody can be used for Immunohistochemistry (1/100-1/200).
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/235_G3_2_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria & microtubules.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/235_G3_2_selected.jpg
Figure 1 Colon
(Enterocytes - Peripheral nerve/ganglion Staining: Low Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_9_3.jpg
(Enterocytes - Peripheral nerve/ganglion Staining: Low Intensity: Weak)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_9_3.jpg
Figure 2 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_6_6.jpg
Figure 3 High expression in smooth muscle
(Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_B_4_7.jpg
(Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_B_4_7.jpg
Figure 4 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, CACO-2, EFO-21, fHDF/TERT166, hTERT-RPE1, LHCN-M2, U-138 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149591-TAGLN
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149591-TAGLN
Specifications
- Immunogen
- Recombinant human TAGLN.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human TAGLN
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Peyronie Disease; Aortic Dissection
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- Transgelin; SM22-Alpha; Smooth Muscle Protein 22-Alpha; 22 KDa Actin-Binding Protein; Transgelin Variant 2; WS3-10;
- Gene ID
- 6876
- UniProt ID
- Q01995
- Long Name
- Transgelin
- Cellular Localization
- Cytoplasm
- Protein Refseq
- NP_003177.2
- Function
- Actin cross-linking/gelling protein (By similarity).
Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1882CT | Recombinant Mouse anti-Human TAGLN Monoclonal antibody (8C8) | ELISA, WB | |
| HPAB-0127-LSX | Human Anti-TAGLN Recombinant Antibody (clone Fab1630) | ELISA, WB | Human IgG |
| FAMAB-1264CQ | Mouse Anti-TAGLN Recombinant Antibody (clone SAIC-33B-129) | WB, Immuno-MRM, ELISA | Mouse IgG1 |
| VS-0923-FY141 | Recombinant Mouse Anti-TAGLN Antibody (VS-0923-FY141) | ELISA, WB | Mouse IgG1 |
| VS3-XY3517 | Rabbit Anti-TAGLN Recombinant Antibody (clone R02-8A4) | WB, IHC-P | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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