Rabbit Anti-TAGLN Recombinant Antibody (VS13-YC1139)
CAT#: VS13-YC1139
The Rabbit Anti-TAGLN Recombinant Antibody is specific for human TAGLN. TAGLN encodes an actin-binding protein acting as a tumor suppressor, involved in smooth muscle differentiation and contraction, with observed changes linked to tumor progression. The anti-TAGLN antibody can be used for Immunohistochemistry (1/100-1/200).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to mitochondria & microtubules.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/235_G3_2_selected.jpg
Normal Tissue
Figure 1 Colon
Enterocytes - Peripheral nerve/ganglion Staining: Low Intensity: Weak
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_9_3.jpg
Normal Tissue
Figure 2 Testis
Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_A_6_6.jpg
Normal Tissue
Figure 3 High expression in smooth muscle
Smooth muscle cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/19467/45371_B_4_7.jpg
RNA Expression
Figure 4 RNA cell line category: Cell line enhanced (BJ, BJ hTERT+ SV40 Large T+, CACO-2, EFO-21, fHDF/TERT166, hTERT-RPE1, LHCN-M2, U-138 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000149591-TAGLN
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Specifications
- Immunogen
- Recombinant human TAGLN.
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human TAGLN
- Species Reactivity
- Human
- Applications
- IHC-P
- Conjugate
- NONE
- Related Disease
- Peyronie Disease; Aortic Dissection
Product Property
- Clonality
- Monoclonal
- Purification
- Affinity Chromatography purified
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS (pH 7.2) containing 50% Glycerol and 0.5% BSA.
- Preservative
- 0.02% Sodium azide
- Storage
- Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Shipping with ice pack.
Applications
- Application Notes
- Immunohistochemistry (IHC): 1/100-1/200
Target
- Alternative Names
- Transgelin; SM22-Alpha; Smooth Muscle Protein 22-Alpha; 22 KDa Actin-Binding Protein; Transgelin Variant 2; WS3-10;
- Gene ID
- 6876
- UniProt ID
- Q01995
- Long Name
- Transgelin
- Cellular Localization
- Cytoplasm
- Protein Refseq
- NP_003177.2
- Function
- Actin cross-linking/gelling protein (By similarity).
Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence.
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Secondary Antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
See other products for "TAGLN"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1882CT | Recombinant Mouse anti-Human TAGLN Monoclonal antibody (8C8) | ELISA, WB |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-LSX | Human Anti-TAGLN Recombinant Antibody (clone Fab1630) | ELISA, WB | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-LSX-S(P) | Human Anti-TAGLN Recombinant Antibody (clone Fab1630); scFv Fragment | WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0127-LSX-F(E) | Human Anti-TAGLN Recombinant Antibody (clone Fab1630); Fab Fragment | WB | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-1264CQ | Mouse Anti-TAGLN Recombinant Antibody (clone SAIC-33B-129) | WB, Immuno-MRM, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0923-FY141 | Recombinant Mouse Anti-TAGLN Antibody (VS-0923-FY141) | ELISA, WB | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS3-XY3517 | Rabbit Anti-TAGLN Recombinant Antibody (clone R02-8A4) | WB, IHC-P | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0724-YC1175 | AbPlus™ Anti-TAGLN Magnetic Beads (VS-0724-YC1175) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY2245 | Anti-TAGLN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7082 | Anti-Mouse TAGLN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7081 | Anti-Human TAGLN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7083 | Anti-Rat TAGLN Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY7084 | Anti-Porcine TAGLN Immunohistochemistry Kit | IHC |
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