Mouse Anti-TAPBP Recombinant Antibody (clone PaSta1) (CAT#: VS-0724-FY23)
This is a mouse monoclonal antibody that binds to human tapasin. PaSta1 binds to all tapasin molecules, both free and bound to MHC-I. It binds tapasin with a KD value of 1 to 2 nM. PaSta1 binds to tapasin at the top of the N-IgV domain.
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Specifications
- Host Species
- Mouse
- Derivation
- Hybridoma
- Type
- Mouse IgG
- Specificity
- Human Tapasin
- Species Reactivity
- Human
- Clone
- PaSta1
- Applications
- Immunoassay
- Related Disease
- Bare Lymphocyte Syndrome, Type I and Spondyloarthropathy 1
Product Property
- Clonality
- Monoclonal Antibody
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Stabilizer
- No Stabilizers
- Sterility
- 0.2 μM filtered
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- TAP Binding Protein; TAP Binding Protein (Tapasin); TAP-Associated Protein; Tapasin; NGS-17; NGS17
- Gene ID
- 6892
- UniProt ID
- O15533
- Long Name
- TAP Binding Protein
- Cellular Localization
- Endoplasmic reticulum membrane
- Post Translation Modifications
- Glycosylation at Asn253
Ubiquitination at Lys40 and Lys104
Modification sites at PhosphoSitePlus
Glycosylation from GlyConnect TPSN_HUMAN
Glycosylation from GlyGen 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
- Protein Refseq
- XP_011513130.1; XP_047275227.1; XP_047275228.1; XP_054185831.1; XP_054185832.1
- Function
- Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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