Recombinant Anti-Tau (Thr169/175 x AA 218-225) Biparatopic Antibody, Tandem scFv (Clone MHT2 x Clone Tau5) (CAT#: VS-0525-YC177)

• Host Animal 1
• Mouse

• Host Animal 2
• Mouse

• Specificity
• Human Tau

• Species Reactivity
• Human

• Type
• Tandem scFv

• Valency
• 1 + 1

• Clone 1
• MHT2

• Clone 2
• Tau5

• Epitope 1
• Human tau encompassing the threonine 169/175 epitope region

• Epitope 2
• aa 218-225

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• ELISA

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• Tau

• Introduction
• Tau proteins are proteins that stabilize microtubules. They are abunda- nt in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease.

• Alternative Names
• Tau protein; Tau

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